Next departures for Los Angeles to San Luis Obispo on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Los Angeles Union Station
San Luis Obispo
CheapestFastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
AMTRAK Station
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
Next departures for Los Angeles to San Luis Obispo on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Los Angeles Union Station
San Luis Obispo
CheapestFastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
AMTRAK Station
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
Next departures for Los Angeles to San Luis Obispo on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Los Angeles Union Station
San Luis Obispo
CheapestFastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
AMTRAK Station
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
Next departures for Los Angeles to San Luis Obispo on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
Cheapest
Los Angeles Union Station
San Luis Obispo
Fastest
Los Angeles Union Station
San Luis Obispo
No tags
Union Station
AMTRAK Station
No tags
Union Station
AMTRAK Station
No tags
Next departures for Los Angeles to San Luis Obispo on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
Cheapest
Los Angeles Union Station
San Luis Obispo
Fastest
Union Station
AMTRAK Station
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
UCLA
AMTRAK Station
No tags
Next departures for Los Angeles to San Luis Obispo on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Los Angeles Union Station
San Luis Obispo
CheapestFastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
AMTRAK Station
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
Next departures for Los Angeles to San Luis Obispo on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
UCLA
AMTRAK Station
Cheapest
Los Angeles Union Station
San Luis Obispo
Fastest
Union Station
AMTRAK Station
No tags
Greyhound Lines, Inc. + FlixBus
Lankershim/Magnolia - North Hollywood
San Luis Obispo
No tags
Union Station
Cal Poly Vista Grande Dining Complex
No tags
Last refresh of the prices: Today at 9:18 AM PST.
Compare 2 ways to go from Los Angeles to San Luis Obispo
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach San Luis Obispo. The journey takes about 5 hours 25 minutes and with fares starting at just $40, it presents an excellent value for a comfortable ride.
Based on 5594 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $64
Amtrak Los Angeles San Luis Obispo recent customer reviews
The workers on the train and bus were great, as was the ride itself. However, the system was entirely too confusing and the information needed was not readily available.
At the Union station, the Amtrack worker behind the information desk just ignored me for over 10 minutes. This was at around 6pm, and the sign said that desk doesn't close until 10pm. The security guards were the ones helping people instead, and they were clearly used to doing that instead of focusing on security.
Also, when transferring from the train to the bus, there was no clear signage or directions as to where to go. About 30 of us almost boarded the wrong bus, as it was the only one there (our actual bus was 10-15 mins late) and the poor driver had no clear way to tell the entire crowd.
Overall, the workers were amazing (aside from the one at the help desk) but the system was way too confusing, especially considering the lack of help. Many of us were left feeling very lost and confused.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
9901 S La Cienega Blvd, Los Angeles, CA 90045, USA
Stops in San Luis Obispo
A - AMTRAK Station
1730 Santa Rosa St, San Luis Obispo, CA 93401, USAAMTRAK Station
B - San Luis Obispo Bus Stop
1460 Calle Joaquin, San Luis Obispo, CA 93405, USA
Frequently asked questions about traveling from Los Angeles, US to San Luis Obispo by bus
How far is Los Angeles from San Luis Obispo?
About 158 miles (255 km) separate Los Angeles and San Luis Obispo.
What are the departure and arrival stations when taking the bus from Los Angeles to San Luis Obispo?
Most of the buses traveling from Los Angeles to San Luis Obispo leave from Ramirez Street bus stop and arrive at AMTRAK Station. These are the main pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$66
11/18
$50
Today
$50
11/20
$47
11/21
$46
11/22
$46
11/23
$49
11/24
$66
The cheapest trip from Los Angeles, US to San Luis Obispo was searched and found on Nov 21, 2025 with a price of $46
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Los Angeles, US to San Luis Obispo, as early as possible.
You can expect to pay from $46 to $293 for a bus ticket from Los Angeles, US to San Luis Obispo based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2025-11-21.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.