Bus Tickets from Jefferson City, MO to San Diego, CA, US

Next departures

Next departures for Jefferson City to San Diego on October 23
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Jefferson City
San Diego (Old Town-FlixBus)Cheapest
Greyhound Lines, Inc. + FlixBus
Jefferson City
UCSD Health La Jolla StationFastest
Greyhound Lines, Inc. + FlixBus
Jefferson City
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc.
Jefferson City
Greyhound Bus StopNo tags
Greyhound Lines, Inc. + FlixBus
Jefferson City
UCSD Health La Jolla StationNo tags

Last refresh of the prices: Yesterday at 10:13 PM CDT.

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Bus Jefferson City, MO to San Diego, CA, US: Trip Overview

Average Ticket PriceUS$284
Average Bus Trip Duration2d
Number of daily buses10
Earliest bus departure4:50pm
Distance2345 km
Latest bus departure7:15pm

Jefferson City to San Diego Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jefferson City to San Diego.

Bus service from Jefferson City to San Diego will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Jefferson City to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Jefferson City, MO - San Diego, CA, US

  1. How far is Jefferson City from San Diego?

    The distance between Jefferson City and San Diego is around 2346 km (1455 miles).

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-20
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10-21
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Today
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10-23
US$294
10-24
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10-25
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10-26
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10-27
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busbud logoThe cheapest trip from Jefferson City, MO to San Diego, CA, US was searched and found on Oct 23, 2025 with a price of US$294

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jefferson City, MO to San Diego, CA, US, as early as possible.

You can expect to pay from US$294 to US$294 for a bus ticket from Jefferson City, MO to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$294 which is on 2025-10-23.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jefferson City to San Diego but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Jefferson City to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jefferson City to San Diego that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Jefferson City to San Diego while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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