Bus from Chicago to San Diego, CA, US: Tickets & Schedules

Next bus departures

Next departures for Chicago to San Diego on January 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Chicago 95Th & Dan Ryan
San Diego (Old Town-FlixBus)Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
UCSD Health La Jolla StationFastest
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Greyhound Bus StopNo tags
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
San Diego (Old Town-FlixBus)No tags

Last refresh of the prices: Yesterday at 8:18 PM CST.

Compare 2 ways to go from Chicago to San Diego

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach San Diego. The journey takes about 2 days, 42 minutes, and with fares starting at just $262, it presents an excellent value for a comfortable ride.

3train per day
2d Average Duration
2787 kmDistance
254kgCO₂ emissions
Average Price$178 - $1,419Average Duration2d 9h
70kg CO₂e
Average Price$262 - $2,467Average Duration2d
254kg CO₂e

Frequently asked questions about travelling from Chicago to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Chicago to San Diego?

    The cheapest bus tickets from Chicago to San Diego start from $178. The average price for this route is around $285. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Chicago to San Diego?

    The average bus travel time from Chicago to San Diego is 2d 9h, covering a distance of 2785 km. The quickest bus can get you there in 2d 5h and is operated by Greyhound.

  3. Which bus companies service the Chicago to San Diego route?

    Several major bus companies operate on this route with 30 buses available per day, including services from Greyhound, FlixBus.

  4. What are the earliest and latest departure times for the bus from Chicago to San Diego?

    The earliest bus departs from Chicago to San Diego at 12:15am. And the latest bus departs at 11:50pm.

  5. What are the CO₂ emissions for the bus trip from Chicago to San Diego?

    A bus trip from Chicago to San Diego generates an estimated 70 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Chicago to San Diego?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.

  7. Which bus company has the best Wi-Fi from Chicago to San Diego?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Chicago to San Diego?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Chicago to San Diego?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01-25
$220
01-26
$734
Today
$594
01-28
$454
01-29
$291
01-30
$257
01-31
No data
02-01
$300
busbud logoThe cheapest trip from Chicago to San Diego, CA, US was searched and found on Jan 25, 2026 with a price of $220

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Diego, CA, US, as early as possible.

You can expect to pay from $220 to $734 for a bus ticket from Chicago to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $257 which is on 2026-01-30.

What's the cheapest way to go from Chicago to San Diego, CA, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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