Find coaches from Chicago to San Diego, CA, US

Next bus departures

Next departures from Chicago to San Diego on 21 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
537-517 W. Jackson Blvd
Greyhound Bus StopCheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
UCSD Health La Jolla StationFastest
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
San Diego (Old Town-FlixBus)No tags
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc. + FlixBus
Bus
Downtown Greyhound Station
UCSD Health La Jolla StationNo tags

Last refresh of the prices: Today at 13:22 CST.

Compare 2 ways to travel from Chicago to San Diego

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 7 hours 45 minutes and with fares starting at just £93, it presents an excellent value for a comfortable ride.

21bus per day
2d 7hAverage duration
1725 milesDistance
70kgCO₂ emissions
Average price£93 - £455Average duration2d 7h
70kg CO₂e
Average price£146 - £1,211Average duration2d
254kg CO₂e

Frequently asked questions about travelling by bus from Chicago to San Diego, CA, US

  1. What's the distance between Chicago and San Diego by coach?

    The distance between Chicago and San Diego by coach is approximately 1729 miles (2788 km).

  2. What is the best way to go from Chicago to San Diego without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/11
£103
19/11
£354
Today
£120
21/11
£352
22/11
£102
23/11
£102
24/11
No data
25/11
£168
busbud logoThe cheapest trip from Chicago to San Diego, CA, US was searched and found on 22 Nov 2025 with a price of £102

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Diego, CA, US as early as possible.

You can expect to pay from £102 to £358 for a bus ticket from Chicago to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £102, which is on 2025-11-22.

What's the cheapest way to go from Chicago to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

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