Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | Pensacola Airport | CheapestFastest | ||||
| Bus | Tupelo (Brothers Quick Stop) | Pensacola Airport | No tags |
Last refresh of the prices: Last Saturday at 3:35 PM CST.
Get from Tupelo to Pensacola
The journey takes about 1 day, 5 hours 35 minutes and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Tupelo to Pensacola by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Pensacola?
The cheapest bus tickets from Tupelo to Pensacola start from $99. The average price for this route is around $105. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Pensacola?
The average bus trip duration from Tupelo to Pensacola is 1d 5h, covering a distance of 274 miles (442 km). The quickest bus can get you there in 17h 55m and is operated by Greyhound.
Which bus companies service the Tupelo to Pensacola route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Tupelo to Pensacola?
The earliest bus departs from Tupelo to Pensacola at 10:55am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Tupelo to Pensacola?
A bus trip from Tupelo to Pensacola generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Pensacola was searched and found on Jan 10, 2026 with a price of $92To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Pensacola, as early as possible.
You can expect to pay from $92 to $97 for a bus ticket from Tupelo to Pensacola based on the last 2 days. You can expect to find the cheapest price for the trip at $92 which is on 2026-01-13.
