Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | Nashville Bus Station | Cheapest | ||||
| Bus | Tupelo (Brothers Quick Stop) | Nashville Bus Station | Fastest |
Last refresh of the prices: Yesterday at 9:57 AM CST.
Get from Tupelo to Nashville
The journey takes about 10 hours 55 minutes and with fares starting at just $69, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Tupelo to Nashville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Nashville?
The cheapest bus tickets from Tupelo to Nashville start from $69. The average price for this route is around $98. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Nashville?
The average bus trip duration from Tupelo to Nashville is 10h 55m, covering a distance of 171 miles (276 km). The quickest bus can get you there in 6h 50m and is operated by Greyhound.
Which bus companies service the Tupelo to Nashville route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Tupelo to Nashville?
The earliest bus departs from Tupelo to Nashville at 5:35am. And the latest bus departs at 9:35pm.
What are the CO₂ emissions for the bus trip from Tupelo to Nashville?
A bus trip from Tupelo to Nashville generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Nashville, TN was searched and found on Jan 16, 2026 with a price of $96To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Nashville, TN, as early as possible.
