Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound St. Louis New Orleans recent customer reviews
I didn't get to New Orleans on this bus. I got to Baton Rouge at 8pm and was told the next bus was at 5am the following morning. We missed the connecting bus by over an hour. 5 of us caught an uber to New Orleans as we had to get there and didn't want to wait all night for another bus.
2 out of 5 stars
Michelle S.
I made all of my connections. Arrival time was accurate.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 5594 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $136
Frequently asked questions about traveling from St. Louis to New Orleans by bus
How far is St. Louis from New Orleans?
About 599 miles (966 km) separate St. Louis and New Orleans.
What are the departure and arrival stations when taking the bus from St. Louis to New Orleans?
Buses traveling from St. Louis to New Orleans leave from Gateway Station and arrive at Union Passenger Terminal.
What are the best sights and things to do in New Orleans?
Once in New Orleans, you can start exploring the city and discover its surroundings. The top sights and things to do are St. Louis Cathedral, Canal Street, City Park, Audubon Aquarium Of The Americas and Louisiana Children's Museum.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$95
11/18
No data
Today
$114
11/20
$74
11/21
$89
11/22
$89
11/23
No data
11/24
No data
The cheapest trip from St. Louis to New Orleans was searched and found on Nov 20, 2025 with a price of $74
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to New Orleans, as early as possible.
You can expect to pay from $74 to $521 for a bus ticket from St. Louis to New Orleans based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2025-11-20.
Usually Amtrak, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from St. Louis to New Orleans was searched and found on Nov 20, 2025 with a price of $74
