Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Jefferson City | CheapestFastest |
Last refresh of the prices: Today at 8:52 AM CST.
Compare 2 ways to go from St. Louis to Jefferson City
Among the sustainable travel choices, the train stands out as the good way to reach Jefferson City. The journey takes about 2 hours 25 minutes and with fares starting at just $27, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from St. Louis to Jefferson City, MO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Jefferson City?
The cheapest bus tickets from St. Louis to Jefferson City start from $30. The average price for this route is around $33. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Jefferson City?
The average bus trip duration from St. Louis to Jefferson City is 4h 5m, covering a distance of 105 miles (170 km). The quickest bus can get you there in 4h 5m and is operated by Greyhound.
Which bus companies service the St. Louis to Jefferson City route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from St. Louis to Jefferson City?
The earliest bus departs from St. Louis to Jefferson City at 11:55am. And the latest bus departs at 11:55am.
What are the CO₂ emissions for the bus trip from St. Louis to Jefferson City?
A bus trip from St. Louis to Jefferson City generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Jefferson City, MO was searched and found on Dec 4, 2025 with a price of $25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Jefferson City, MO, as early as possible.
You can expect to pay from $25 to $76 for a bus ticket from St. Louis to Jefferson City, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-12-04.
