- St. Louis to Des Moines buses
Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Des Moines | CheapestFastest |
Last refresh of the prices: Yesterday at 8:11 AM CST.
Get from St. Louis to Des Moines
The journey takes about 15 hours 5 minutes and with fares starting at just $100, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Des Moines?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
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Frequently asked questions about traveling from St. Louis to Des Moines by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Des Moines?
The cheapest bus tickets from St. Louis to Des Moines start from $100. The average price for this route is around $132. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Des Moines?
The average bus trip duration from St. Louis to Des Moines is 15h 5m, covering a distance of 274 miles (441 km). The quickest bus can get you there in 9h 10m and is operated by Burlington Trailways.
Which bus companies service the St. Louis to Des Moines route?
Several major bus companies operate on this route with 1 buses available per day, including services from Burlington Trailways, Greyhound.
What is the earliest and latest departure time for the bus from St. Louis to Des Moines?
The earliest bus departs from St. Louis to Des Moines at 11:30pm. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Des Moines?
A bus trip from St. Louis to Des Moines generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from St. Louis to Des Moines?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from St. Louis to Des Moines?
Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company has the most timely service from St. Louis to Des Moines?
According to Busbud traveller reviews, the most timely bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Des Moines?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.







