Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Florenc | CheapestFastest |
Last refresh of the prices: Last Monday at 6:37 PM CET.
Compare 2 ways to go from Rome to Prague
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Prague. The journey takes about 14 hours and with fares starting at just $64, it presents an excellent value for a comfortable ride.
1carpool per day
14hAverage Duration
573 milesDistance
39kgCO₂ emissions
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$58 - $245 | Average Duration1d | 23kg CO₂e | ||
Carpool | Average Price$64 - $75 | Average Duration14h | 39kg CO₂e |
Where are the popular stops in Rome and Prague?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - BAviatická, 161 08, Praha 6, Czechia
- CTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- DChlumecká, 198 00 Praha 20, Czech Republic
- EKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
CZ bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia
Frequently asked questions about traveling from Rome to Prague by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
No data
11/25
$82
Today
$76
11/27
No data
11/28
No data
11/29
No data
11/30
No data
12/01
No data
The cheapest trip from Rome to Prague was searched and found on Nov 26, 2025 with a price of $76To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Prague, as early as possible.
