Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Tiburtina Bus Station | Florenc | CheapestFastest |
Last refresh of the prices: Last Monday at 6:37 PM CET.
Compare 2 ways to travel from Rome to Prague
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 14 hours and with fares starting at just R 1 114, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 1 014 - R 4 304 | Average duration1d | 23kg CO₂e | ||
Carpool | Average priceR 1 114 - R 1 308 | Average duration14h | 39kg CO₂e |
Where are the popular stops in Rome and Prague?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - BAviatická, 161 08, Praha 6, Czechia
- CTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- DChlumecká, 198 00 Praha 20, Czech Republic
- EKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Frequently asked questions about travelling from Rome to Prague by bus
How much does a bus ticket from Rome to Prague cost?
The bus ticket price from Rome to Prague starts at R 1 014. The best way to find cheap bus tickets from Rome to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Rome to Prague?
The average travel time between Rome and Prague is around 1d , although the fastest bus will take about 20h 10m. This is the time it takes to travel the 925 km that separates the two cities.
How many daily bus connections are there between Rome and Prague?
The number of buses from Rome to Prague can differ depending on the day of the week. On average, there are 48 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Rome to Prague by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Rome to Prague?
When taking the bus from Rome to Prague, you can travel comfortably and safely with FlixBus, RegioJet.
What are the departure and arrival stations when taking the bus from Rome to Prague?
Buses travelling between Rome and Prague leave from Rome Tiburtina Bus Station or Rome Ciampino Airport and arrive at Zličín, PRG Airport, Tomíčkova.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Prague was searched and found on 26 Nov 2025 with a price of R 1 330To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Prague as early as possible.
