Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags |
Get from Pittsburgh to Des Moines
The journey takes about 18 hours 55 minutes and with fares starting at just $139, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and Des Moines?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Pittsburgh to Des Moines by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to Des Moines was searched and found on Nov 24, 2025 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Des Moines, as early as possible.
Top traveled bus routes
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