Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags | ||||
| Bus | Pittsburgh Intermodal Station | Des Moines (Subway) | No tags |
Get from Pittsburgh to Des Moines
The journey takes about 18 hours 55 minutes, and with fares starting at just R 2 461, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pittsburgh and Des Moines?
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Based on 87393 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 568
Frequently asked questions about travelling from Pittsburgh to Des Moines by bus
How much does a bus ticket from Pittsburgh to Des Moines cost?
The bus ticket price from Pittsburgh to Des Moines starts at R 2 461. The best way to find cheap bus tickets from Pittsburgh to Des Moines is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Pittsburgh to Des Moines?
The average travel time between Pittsburgh and Des Moines is around 18h 55m, although the fastest bus will take about 18h 55m. This is the time it takes to travel the 1150 km that separates the two cities.
How many daily bus connections are there between Pittsburgh and Des Moines?
The number of buses from Pittsburgh to Des Moines can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Pittsburgh to Des Moines by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Pittsburgh to Des Moines?
When taking the bus from Pittsburgh to Des Moines, you can travel comfortably and safely with Greyhound.
What are the departure and arrival stations when taking the bus from Pittsburgh to Des Moines?
Buses travelling between Pittsburgh and Des Moines leave from Intermodal Station or Sennott Square and arrive at Jefferson/Trailways Depot, 1514 East Grand Ave.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pittsburgh to Des Moines was searched and found on 24 Nov 2025 with a price of R 2 155To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Des Moines as early as possible.
