Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Orlando to Louisville by bus
What is the distance between Orlando and Louisville?
The distance between the two cities is 717 miles (1156 km).
What are the departure and arrival stations when taking the bus from Orlando to Louisville?
If you're headed to Louisville from Orlando, chances are that your bus will depart from Orlando Bus Station and arrive at Louisville Greyhound Bus Station. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
$143
11/25
$261
Today
$181
11/27
No data
11/28
$155
11/29
No data
11/30
No data
12/01
$162
The cheapest trip from Orlando to Louisville was searched and found on Nov 24, 2025 with a price of $143
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Louisville, as early as possible.
You can expect to pay from $143 to $277 for a bus ticket from Orlando to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $155 which is on 2025-11-28.
The cheapest trip from Orlando to Louisville was searched and found on Nov 24, 2025 with a price of $143
