How much is the bus ticket from Chicago to Louisville?

The cheapest bus tickets from Chicago to Louisville start from $39. The average price for this route is around $58. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Chicago to Louisville?

The average bus trip duration from Chicago to Louisville is 6h 50m, covering a distance of 269 miles (434 km). The quickest bus can get you there in 5h 45m and is operated by FlixBus .

Which bus companies service the Chicago to Louisville route?

Several major bus companies operate on this route with 15 buses available per day, including services from Greyhound , FlixBus , Amtrak .

What is the earliest and latest departure time for the bus from Chicago to Louisville?

The earliest bus departs from Chicago to Louisville at 5:25am. And the latest bus departs at 11:40pm.

What are the CO₂ emissions for the bus trip from Chicago to Louisville?

A bus trip from Chicago to Louisville generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Chicago to Louisville?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5696 reviews.

Which bus company has the best Wi-Fi from Chicago to Louisville?

Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company has the most timely service from Chicago to Louisville?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Chicago to Louisville?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus Chicago to Louisville from $37 | Refundable Tickets

Next bus departures

Next departures for Chicago to Louisville on January 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	5:25am	Chicago 95Th & Dan Ryan	7h	1:25pm	Louisville, KY	Cheapest
	Bus	6:40pm	Chicago 95Th & Dan Ryan	5h 45m	1:25am	Louisville, KY	Fastest
	Bus	10:00am	Chicago (Union Station), IL	6h 50m	5:50pm	Louisville, KY	No tags
	Bus	6:10am	Downtown Greyhound Station	6h 15m	1:25pm	Louisville, KY	No tags
	Bus	1:00pm	Downtown Greyhound Station	7h 50m	9:50pm	Louisville, KY	No tags

Next departures for Chicago to Louisville on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	5:25am	Chicago 95Th & Dan Ryan	7h	1:25pm	Louisville, KY	Cheapest
	Bus	6:40pm	Chicago 95Th & Dan Ryan	5h 45m	1:25am	Louisville, KY	Fastest
	Bus	10:00am	Chicago (Union Station), IL	6h 50m	5:50pm	Louisville, KY	No tags
	Bus	6:10am	Downtown Greyhound Station	6h 15m	1:25pm	Louisville, KY	No tags
	Bus	1:00pm	Downtown Greyhound Station	7h 50m	9:50pm	Louisville, KY	No tags

Next departures for Chicago to Louisville on January 18
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:40am	Downtown Greyhound Station	7h 5m	5:45pm	Louisville, KY	Cheapest
Bus	6:40pm	Chicago 95Th & Dan Ryan	5h 45m	1:25am	Louisville, KY	Fastest
Bus	10:00am	Chicago (Union Station), IL	6h 50m	5:50pm	Louisville, KY	No tags
Bus	6:10am	Downtown Greyhound Station	6h 15m	1:25pm	Louisville, KY	No tags
Bus	1:00pm	Downtown Greyhound Station	7h 50m	9:50pm	Louisville, KY	No tags

Next departures for Chicago to Louisville on January 19
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:40am	Downtown Greyhound Station	7h 5m	5:45pm	Louisville, KY	Cheapest
Bus	6:40pm	Chicago 95Th & Dan Ryan	5h 45m	1:25am	Louisville, KY	Fastest
Bus	10:00am	Chicago (Union Station), IL	6h 50m	5:50pm	Louisville, KY	No tags
Bus	6:10am	Downtown Greyhound Station	6h 15m	1:25pm	Louisville, KY	No tags
Bus	1:00pm	Downtown Greyhound Station	7h 50m	9:50pm	Louisville, KY	No tags

Next departures for Chicago to Louisville on January 20
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:40am	Downtown Greyhound Station	7h 5m	5:45pm	Louisville, KY	Cheapest
Bus	6:40pm	Chicago 95Th & Dan Ryan	5h 45m	1:25am	Louisville, KY	Fastest
Bus	10:00am	Chicago (Union Station), IL	6h 50m	5:50pm	Louisville, KY	No tags
Bus	6:10am	Downtown Greyhound Station	6h 15m	1:25pm	Louisville, KY	No tags
Bus	1:00pm	Downtown Greyhound Station	7h 50m	9:50pm	Louisville, KY	No tags

Last refresh of the prices: Last Monday at 9:23 PM CST.

Get from Chicago to Louisville

This route is served by bus only

The journey takes about 6 hours 50 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.

15bus per day

6h 50mAverage Duration

269 milesDistance

11kgCO₂ emissions

Where are the popular stops in Chicago and Louisville?

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page Map
B
Chicago O'Hare International Airport
Visit page Map
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
Map
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
Map
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
Map
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Map

Stops in Louisville

A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
Map

Compare bus companies

Greyhound

3.5/587,501 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Chicago Louisville recent customer reviews

Indianapolis Greyhound staff was extremely disorganized and did a very poor job of keeping travelers informed.

Hayley F.

August 29, 2019

The bus was not as clean and the wifi doesn't work.Though it is free it should work.

Sujit J.

September 10, 2017

Nice all around

Maurice G.

October 22, 2025

FlixBus

3.5/512,049 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Amtrak

4/55,735 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Chicago to Louisville by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Chicago to Louisville?
The cheapest bus tickets from Chicago to Louisville start from $39. The average price for this route is around $58. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Louisville?
The average bus trip duration from Chicago to Louisville is 6h 50m, covering a distance of 269 miles (434 km). The quickest bus can get you there in 5h 45m and is operated by FlixBus.
Which bus companies service the Chicago to Louisville route?
Several major bus companies operate on this route with 15 buses available per day, including services from Greyhound, FlixBus, Amtrak.
What is the earliest and latest departure time for the bus from Chicago to Louisville?
The earliest bus departs from Chicago to Louisville at 5:25am. And the latest bus departs at 11:40pm.
What are the CO₂ emissions for the bus trip from Chicago to Louisville?
A bus trip from Chicago to Louisville generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Louisville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5696 reviews.
Which bus company has the best Wi-Fi from Chicago to Louisville?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Chicago to Louisville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Louisville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/12

$72

01/13

$55

Today

$55

01/15

$66

01/16

$45

01/17

$45

01/18

$45

01/19

$43

The cheapest trip from Chicago to Louisville was searched and found on Jan 19, 2026 with a price of $43

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Louisville, as early as possible.

You can expect to pay from $43 to $126 for a bus ticket from Chicago to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $43 which is on 2026-01-19.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.