Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Chicago Louisville recent customer reviews
Indianapolis Greyhound staff was extremely disorganized and did a very poor job of keeping travelers informed.
2 out of 5 stars
Hayley F.
The bus was not as clean and the wifi doesn't work.Though it is free it should work.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 5608 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $87
Frequently asked questions about traveling from Chicago to Louisville by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Louisville?
The cheapest bus tickets from Chicago to Louisville start from $30. The average price for this route is around $54. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Louisville?
The average bus trip duration from Chicago to Louisville is 6h 45m, covering a distance of 259 miles (418 km). The quickest bus can get you there in 5h 5m and is operated by Greyhound.
Which bus companies service the Chicago to Louisville route?
Several major bus companies operate on this route with 18 buses available per day, including services from Greyhound, FlixBus, Amtrak.
What is the earliest and latest departure time for the bus from Chicago to Louisville?
The earliest bus departs from Chicago to Louisville at 12:30am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Chicago to Louisville?
A bus trip from Chicago to Louisville generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Louisville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Chicago to Louisville?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Chicago to Louisville?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Louisville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/25
$87
11/26
$82
Today
$75
11/28
$71
11/29
$73
11/30
$128
12/01
$82
12/02
$42
The cheapest trip from Chicago to Louisville was searched and found on Dec 2, 2025 with a price of $42
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Louisville, as early as possible.
You can expect to pay from $42 to $202 for a bus ticket from Chicago to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2025-12-02.
Usually FlixBus, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Chicago to Louisville was searched and found on Dec 2, 2025 with a price of $42
