Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Louisville, KY | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Louisville, KY | Fastest | ||||
 | Bus | Orlando Bus Station | Louisville, KY | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Louisville, KY | No tags | ||||
| Bus | Orlando Bus Station | Louisville, KY | No tags |
Last refresh of the prices: 2026-01-15 EST.
Get from Orlando to Louisville
The journey takes about 19 hours 30 minutes, and with fares starting at just $120, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Louisville?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Louisville
- A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
Compare bus companies
Frequently asked questions about travelling from Orlando to Louisville by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Louisville?
The cheapest bus tickets from Orlando to Louisville start from $120. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Louisville?
The average bus travel time from Orlando to Louisville is 19h 30m, covering a distance of 1163 km. The quickest bus can get you there in 17h 30m and is operated by Greyhound.
Which bus companies service the Orlando to Louisville route?
What are the earliest and latest departure times for the bus from Orlando to Louisville?
The earliest bus departs from Orlando to Louisville at 5:15am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Orlando to Louisville?
A bus trip from Orlando to Louisville generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Orlando to Louisville?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12050 reviews.
Which bus company has the best Wi-Fi from Orlando to Louisville?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Orlando to Louisville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Louisville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Louisville was searched and found on Jan 27, 2026 with a price of $155To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Louisville, as early as possible.
You can expect to pay from $155 to $326 for a bus ticket from Orlando to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $155 which is on 2026-01-27.
