Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Orlando Bus Station | Louisville, KY | Cheapest | ||||
 | Bus | Orlando Bus Station | Louisville, KY | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Louisville, KY | No tags | ||||
| Bus | Orlando Bus Station | Louisville, KY | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Louisville, KY | No tags |
Last refresh of the prices: Last Monday at 12:00 PM EST.
Get from Orlando to Louisville
The journey takes about 18 hours 55 minutes, and with fares starting at just $149, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Louisville?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Louisville
- A
Louisville Greyhound Bus Station
720 W Muhammad Ali Blvd, Louisville, KY 40203
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Frequently asked questions about travelling from Orlando to Louisville by bus
What is the distance between Orlando and Louisville?
Orlando and Louisville are 1156 km (717 miles) apart.
What are the departure and arrival locations for buses traveling from Orlando to Louisville?
Buses departing from Orlando Bus Station in Orlando will take you to Louisville Greyhound Bus Station in Louisville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Louisville was searched and found on Nov 28, 2025 with a price of $224To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Louisville, as early as possible.
You can expect to pay from $224 to $399 for a bus ticket from Orlando to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at $224 which is on 2025-11-28.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
