Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Houston, US to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to San Ysidro?
The cheapest bus tickets from Houston to San Ysidro start from $132. The average price for this route is around $306. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to San Ysidro?
The average bus trip duration from Houston to San Ysidro is 2d , covering a distance of 1288 miles (2077 km). The quickest bus can get you there in 1d 12h and is operated by Greyhound.
Which bus companies service the Houston to San Ysidro route?
Several major train operators operate on this route with 15 trains available per day.
What is the earliest and latest departure time for the bus from Houston to San Ysidro?
The earliest bus departs from Houston to San Ysidro at 2:00am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to San Ysidro?
A bus trip from Houston to San Ysidro generates an estimated 52 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
01/10
$227
01/11
$307
Today
$264
01/13
$306
01/14
No data
01/15
$273
01/16
$289
01/17
$279
The cheapest trip from Houston, US to San Ysidro, CA was searched and found on Jan 10, 2026 with a price of $227
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to San Ysidro, CA, as early as possible.
You can expect to pay from $227 to $307 for a bus ticket from Houston, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $273 which is on 2026-01-15.
The cheapest trip from Houston, US to San Ysidro, CA was searched and found on Jan 10, 2026 with a price of $227
