Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | The Woodlands - Windvale Center | San Ysidro Bus terminal | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | San Ysidro Bus terminal | Fastest | ||||
 | Bus | Houston Bus Station | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Gray & Smith | San Ysidro Bus terminal | No tags | ||||
Valley Transit + Greyhound Lines, Inc. | Bus | Hillcroft Ave & Southwest Freeway | San Ysidro Bus terminal | No tags |
Last refresh of the prices: Last Tuesday at 8:10 AM CST.
Get from Houston to San Ysidro
The journey takes about 2 days, 15 minutes, and with fares starting at just R 2 206, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and San Ysidro?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Compare bus companies
Based on 87508 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 206
Frequently asked questions about travelling from Houston, US to San Ysidro, CA by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Houston to San Ysidro?
The cheapest bus tickets from Houston to San Ysidro start at R 2 206. The average price for this route is around R 5 006. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Houston to San Ysidro?
The average bus journey time from Houston to San Ysidro is 2d , covering a distance of 2077 km. The fastest bus gets you there in 1d 12h and is operated by Greyhound.
Which bus companies service the Houston to San Ysidro route?
Several major bus companies operate on this route with 17 buses available per day.
What is the earliest and latest departure time for the bus from Houston to San Ysidro?
The earliest bus departs from Houston to San Ysidro at 02:00. And the latest bus departs at 23:20.
What are the CO₂ emissions for the bus trip from Houston to San Ysidro?
A bus trip from Houston to San Ysidro produces an estimated 52 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to San Ysidro, CA was searched and found on 22 Jan 2026 with a price of R 3 162To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to San Ysidro, CA as early as possible.
You can expect to pay from R 3 162 to R 5 062 for a bus ticket from Houston, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 162, which is on 2026-01-22.
