Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Valley Transit + Greyhound Lines, Inc. + FlixBus | Bus | Hillcroft Ave & Southwest Freeway | San Ysidro Greyhound Bus Station | Cheapest | ||||
 | Bus | Houston Bus Station | San Ysidro Bus terminal | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | San Ysidro Bus terminal | No tags | ||||
FlixBus + Valley Transit + Greyhound Lines, Inc. | Bus | Downtown Gray & Smith | San Ysidro Bus terminal | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Houston Bus Station | San Ysidro Bus terminal | No tags |
Last refresh of the prices: Last Saturday at 12:53 AM CST.
Get from Houston to San Ysidro
The journey takes about 2 days, 15 minutes, and with fares starting at just $187, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and San Ysidro?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Compare bus companies
Based on 87497 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $187
Frequently asked questions about travelling from Houston, US to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to San Ysidro?
The cheapest bus tickets from Houston to San Ysidro start from $187. The average price for this route is around $435. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to San Ysidro?
The average bus travel time from Houston to San Ysidro is 2d , covering a distance of 2077 km. The quickest bus can get you there in 1d 12h and is operated by Greyhound.
Which bus companies service the Houston to San Ysidro route?
Several major bus companies operate on this route with 15 buses available per day.
What are the earliest and latest departure times for the bus from Houston to San Ysidro?
The earliest bus departs from Houston to San Ysidro at 2:00am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to San Ysidro?
A bus trip from Houston to San Ysidro generates an estimated 52 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to San Ysidro, CA was searched and found on Jan 10, 2026 with a price of $323To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to San Ysidro, CA, as early as possible.
You can expect to pay from $323 to $436 for a bus ticket from Houston, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $389 which is on 2026-01-15.
