How much is the bus ticket from Harrisburg to Chicago?

The cheapest bus tickets from Harrisburg to Chicago start from $68. The average price for this route is around $130. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Harrisburg to Chicago?

The average bus trip duration from Harrisburg to Chicago is 18h 10m, covering a distance of 571 miles (920 km). The quickest bus can get you there in 14h 45m and is operated by Greyhound .

Which bus companies service the Harrisburg to Chicago route?

Several major bus companies operate on this route with 8 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Harrisburg to Chicago?

The earliest bus departs from Harrisburg to Chicago at 2:30am. And the latest bus departs at 8:15pm.

What are the CO₂ emissions for the bus trip from Harrisburg to Chicago?

A bus trip from Harrisburg to Chicago generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Harrisburg to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87387 reviews.

Which bus company has the best Wi-Fi from Harrisburg to Chicago?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Harrisburg to Chicago?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Harrisburg to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Harrisburg to Chicago from $79 | Refundable Tickets

Next bus departures

Next departures for Harrisburg to Chicago on November 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	2:30am	Harrisburg Bus Station	20h 55m	10:25pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	8:15pm	Harrisburg Bus Station	14h 45m	10:00am	Downtown Greyhound Station	Fastest
	Bus	2:30am	Harrisburg Bus Station	18h 35m	8:05pm	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:25am	Harrisburg Bus Station	19h 45m	6:10am	Downtown Greyhound Station	No tags
	Bus	8:15pm	Harrisburg Bus Station	18h 55m	2:10pm	537-517 W. Jackson Blvd	No tags

Next departures for Harrisburg to Chicago on December 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	8:15pm	Harrisburg Bus Station	18h 10m	1:25pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	8:15pm	Harrisburg Bus Station	14h 45m	10:00am	Downtown Greyhound Station	Fastest
	Bus	2:30am	Harrisburg Bus Station	18h 35m	8:05pm	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	2:05pm	Harrisburg Bus Station	20h 45m	9:50am	Chicago 95Th & Dan Ryan	No tags
	Bus	2:05pm	Harrisburg Bus Station	19h 10m	8:15am	Downtown Greyhound Station	No tags

Next departures for Harrisburg to Chicago on December 2
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	8:15pm	Harrisburg Bus Station	18h 10m	1:25pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	8:15pm	Harrisburg Bus Station	14h 45m	10:00am	Downtown Greyhound Station	Fastest
	Bus	2:30am	Harrisburg Bus Station	18h 35m	8:05pm	Downtown Greyhound Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	2:05pm	Harrisburg Bus Station	20h 45m	9:50am	Chicago 95Th & Dan Ryan	No tags
	Bus	2:05pm	Harrisburg Bus Station	19h 10m	8:15am	Downtown Greyhound Station	No tags

Last refresh of the prices: Today at 12:09 AM EST.

Compare 2 ways to go from Harrisburg to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 18 hours 10 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.

8bus per day

18h 10mAverage Duration

571 milesDistance

23kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$68 - $301	Average Duration18h 10m	CO₂ emissions 23kg CO₂e
Train	Average Price$103 - $315	Average Duration20h 36m	CO₂ emissions 84kg CO₂e

Where are the popular stops in Harrisburg and Chicago?

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/587,408 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,475 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Harrisburg to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Harrisburg to Chicago?
The cheapest bus tickets from Harrisburg to Chicago start from $68. The average price for this route is around $130. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Chicago?
The average bus trip duration from Harrisburg to Chicago is 18h 10m, covering a distance of 571 miles (920 km). The quickest bus can get you there in 14h 45m and is operated by Greyhound.
Which bus companies service the Harrisburg to Chicago route?
Several major bus companies operate on this route with 8 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Harrisburg to Chicago?
The earliest bus departs from Harrisburg to Chicago at 2:30am. And the latest bus departs at 8:15pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Chicago?
A bus trip from Harrisburg to Chicago generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Harrisburg to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Harrisburg to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Harrisburg to Chicago?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Harrisburg to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/27

$114

11/28

$146

Today

$244

11/30

$284

12/01

$160

12/02

$140

12/03

$84

12/04

$82

The cheapest trip from Harrisburg to Chicago was searched and found on Dec 4, 2025 with a price of $82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Chicago, as early as possible.

You can expect to pay from $82 to $347 for a bus ticket from Harrisburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $82 which is on 2025-12-04.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.