Next departures for Guadalajara to San Luis Potosí on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
ORIENTE + Transportes Frontera
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Cheapest
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Fastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Next departures for Guadalajara to San Luis Potosí on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Cheapest
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Fastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Next departures for Guadalajara to San Luis Potosí on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Cheapest
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Fastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Next departures for Guadalajara to San Luis Potosí on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
CheapestFastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Bus
Central Camionera Poniente
Terminal San Luis Potosi
No tags
Next departures for Guadalajara to San Luis Potosí on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Cheapest
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Fastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Next departures for Guadalajara to San Luis Potosí on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Futura + Transportes Frontera
Bus
Terminal Zapopan
San Luis-Guadalajara 128
Cheapest
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Fastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Next departures for Guadalajara to San Luis Potosí on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
CheapestFastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Bus
Central Camionera Poniente
Terminal San Luis Potosi
No tags
Next departures for Guadalajara to San Luis Potosí on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Cheapest
Bus
Nueva Central Camionera de Guadalajara
San Luis-Guadalajara 128
Fastest
Bus
Terminal Zapopan
Central de Autobuses
No tags
Bus
Nueva Central Camionera de Guadalajara
Central de Autobuses
No tags
Bus
Guadalajara Central Bus Station
San Luis Potosí Boulevard San Luis
No tags
Last refresh of the prices: Yesterday at 11:31 PM CST.
Compare 2 ways to go from Guadalajara to San Luis Potosí
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach San Luis Potosí. The journey takes about 4 hours 10 minutes and with fares starting at just $16, it presents an excellent value for a comfortable ride.
Based on 41 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. ORIENTE ticket prices on this trip start at $54
ORIENTE Guadalajara San Luis Potosí recent customer reviews
I bought it as a direct journey but the bus stopped many times along the way. The driver was talking to a woman sitting on the step beside him most of the way, holding her hand instead of having his hands and focus on the road.
Based on 214 reviews, the company was rated 4.5 stars on Busbud. Travelers were especially satisfied with the cleanliness and the staff but often complained with the wifi. ETN ticket prices on this trip start at $64
Based on 734 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Futura ticket prices on this trip start at $56
Primera Plus offers 1 daily buses from Guadalajara to San Luis Potosí. Though the average price for this trip is $51, you can find tickets starting at $50. The trip between the two cities usually takes about 347.
Based on 160 reviews, the company was rated 3.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Chihuahuenses ticket prices on this trip start at $92
Based on 20 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Turistar ticket prices on this trip start at $119
Based on 41 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. ORIENTE ticket prices on this trip start at $54
ORIENTE Guadalajara San Luis Potosí recent customer reviews
I bought it as a direct journey but the bus stopped many times along the way. The driver was talking to a woman sitting on the step beside him most of the way, holding her hand instead of having his hands and focus on the road.
Based on 167 reviews, the company was rated 2.5 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the wifi. Elite ticket prices on this trip start at $56
Based on 23 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the value for money and the ticket access but often complained with the wifi. Rojo de los Altos ticket prices on this trip start at $38
Based on 44 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the seats and the staff but often complained with the wifi. Anahuac ticket prices on this trip start at $40
Based on 1 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the cleanliness. Bonilla Tours ticket prices on this trip start at $27
Based on 22 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the timeliness. Valle del Guadiana ticket prices on this trip start at $37
Based on 12 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the timeliness. Estrella del Norte ticket prices on this trip start at $36
Based on 361 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the staff but often complained with the wifi. Diamante ticket prices on this trip start at $48
Based on 257 reviews, the company was rated 2.8 stars on Busbud. Travelers were especially satisfied with the seats and the staff but often complained with the wifi. Pacifico ticket prices on this trip start at $39
Based on 15 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the seats and the cleanliness but often complained with the timeliness. ELITE SELECT ticket prices on this trip start at $113
Based on 139 reviews, the company was rated 2.4 stars on Busbud. Travelers were especially satisfied with the temperature and the staff but often complained with the wifi. Transportes Frontera ticket prices on this trip start at $41
Based on 32 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Aguacaliente ticket prices on this trip start at $105
Carretera México, Km 2.5, s/n (Col. Santa Fe Sur), 78390 San Luis Potosi
C - Avenida Mexico #1147
Avenida Mexico #1147, De Tequisquiapan, 78230 San Luis, S.L.P., Mexico
Frequently asked questions about traveling from Guadalajara, MX to San Luis Potosí by bus
What is the distance between Guadalajara and San Luis Potosí?
Guadalajara and San Luis Potosí are 186 miles (300 km) apart.
What are the departure and arrival stations when taking the bus from Guadalajara to San Luis Potosí?
If you're headed to San Luis Potosí from Guadalajara, chances are that your bus will depart from Nueva Central and arrive at Central de Autobuses. These are the most popular departure and arrival locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$40
11/17
$40
Today
$32
11/19
$32
11/20
$32
11/21
$32
11/22
$32
11/23
$32
The cheapest trip from Guadalajara, MX to San Luis Potosí was searched and found on Nov 18, 2025 with a price of $32
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guadalajara, MX to San Luis Potosí, as early as possible.
You can expect to pay from $32 to $69 for a bus ticket from Guadalajara, MX to San Luis Potosí based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-11-19.
Usually ETN will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.