Bus Tickets from San Luis Potosí to Guadalajara, MX
Next bus departures
Next departures for San Luis Potosí to Guadalajara on November 21
Operated by
Vehicle type
Departure time
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Trip duration
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Recommended
Price and booking link
Bus
Terminal San Luis Potosi
Central Camionera Poniente
Cheapest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
Fastest
Bus
San Luis Potosí Boulevard San Luis
Zapopan Central de Autobuses (Guadalajara)
No tags
Turistar + ETN
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Next departures for San Luis Potosí to Guadalajara on November 22
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Arrival location
Recommended
Price and booking link
Primera Plus + SKPT de Viaje
Bus
Terminal San Luis Potosi
Hotel RIU Plaza Guadalajara
Cheapest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
Fastest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Bus
Terminal San Luis Potosi
Central Camionera Poniente
No tags
Primera Plus + SKPT de Viaje
Bus
Terminal San Luis Potosi
Hotel RIU Plaza Guadalajara
No tags
Next departures for San Luis Potosí to Guadalajara on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal San Luis Potosi
Central Camionera Poniente
Cheapest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
Fastest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Primera Plus + SKPT de Viaje
Bus
Terminal San Luis Potosi
Hotel RIU Plaza Guadalajara
No tags
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Next departures for San Luis Potosí to Guadalajara on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal San Luis Potosi
Central Camionera Poniente
Cheapest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
Fastest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Primera Plus + SKPT de Viaje
Bus
Terminal San Luis Potosi
Hotel RIU Plaza Guadalajara
No tags
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Next departures for San Luis Potosí to Guadalajara on November 25
Operated by
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Departure time
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Arrival location
Recommended
Price and booking link
Bus
San Luis-Guadalajara 128
Nueva Central Camionera de Guadalajara
Cheapest
Bus
San Luis-Guadalajara 128
Nueva Central Camionera de Guadalajara
Fastest
Bus
Central de Autobuses
Nueva Central Camionera de Guadalajara
No tags
Bus
Central de Autobuses
Nueva Central Camionera de Guadalajara
No tags
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Next departures for San Luis Potosí to Guadalajara on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal San Luis Potosi
Central Camionera Poniente
Cheapest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
Fastest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Bus
Terminal San Luis Potosi
Central Camionera Poniente
No tags
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Next departures for San Luis Potosí to Guadalajara on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal San Luis Potosi
Central Camionera Poniente
Cheapest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
Fastest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Bus
Terminal San Luis Potosi
Central Camionera Poniente
No tags
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Next departures for San Luis Potosí to Guadalajara on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal San Luis Potosi
Central Camionera Poniente
Cheapest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
Fastest
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Bus
Terminal San Luis Potosi
Central Camionera Poniente
No tags
Bus
San Luis Potosí Boulevard San Luis
Guadalajara Central Bus Station
No tags
Last refresh of the prices: Today at 3:31 PM CST.
Compare 2 ways to go from San Luis Potosí to Guadalajara
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Guadalajara. The journey takes about 4 hours 10 minutes and with fares starting at just $17, it presents an excellent value for a comfortable ride.
Based on 41 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. ORIENTE ticket prices on this trip start at $12
ORIENTE San Luis Potosí Guadalajara recent customer reviews
The bus itself was fine. I chose the wrong route personally. Instead of going straight from San Luis Potosí to Guadalajara, we had multiple stops. The 4 hour trip took 7 hours total. Also any bus I have taken before the toilet flushes but this one did not so anyone who used the toilet their “fluids” stayed in the toilet to the point everything sloshed out into the floor of the bathroom and bus so the entire bus stank like excrement. I’d probably travel by bus again but try to go with a higher end company.
2 out of 5 stars
Abigail R.
Be very careful with your booking location - I thought my bus was leaving from the central bus station but it turns out the actual point of departure was 30 minutes away, so I ended up missing my bus and needing to buy another ticket.
Based on 216 reviews, the company was rated 4.5 stars on Busbud. Travelers were especially satisfied with the cleanliness and the staff but often complained with the wifi. ETN ticket prices on this trip start at $64
Based on 735 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Futura ticket prices on this trip start at $56
Primera Plus offers 1 daily departures, and you can find tickets starting at $50. The quickest ride takes around 388. Primera Plus offers a cost-effective solution to get you where you need to be.
Based on 34 reviews, the company was rated 1.7 stars on Busbud. Travelers were especially satisfied with the cleanliness and the staff but often complained with the wifi. SKPT de Viaje ticket prices on this trip start at $73
Based on 23 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the value for money and the ticket access but often complained with the wifi. Rojo de los Altos ticket prices on this trip start at $50
Based on 160 reviews, the company was rated 3.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Chihuahuenses ticket prices on this trip start at $57
Based on 32 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Aguacaliente ticket prices on this trip start at $56
Based on 20 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Turistar ticket prices on this trip start at $118
Based on 139 reviews, the company was rated 2.4 stars on Busbud. Travelers were especially satisfied with the temperature and the staff but often complained with the wifi. Transportes Frontera ticket prices on this trip start at $38
Based on 362 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the staff but often complained with the wifi. Diamante ticket prices on this trip start at $78
Based on 22 reviews, the company was rated 2.6 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the timeliness. Valle del Guadiana ticket prices on this trip start at $48
Based on 44 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the seats and the staff but often complained with the wifi. Anahuac ticket prices on this trip start at $71
Based on 167 reviews, the company was rated 2.5 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the wifi. Elite ticket prices on this trip start at $50
Based on 12 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the timeliness. Estrella del Norte ticket prices on this trip start at $78
Frequently asked questions about traveling from San Luis Potosí to Guadalajara, MX by bus
How far is San Luis Potosí from Guadalajara?
San Luis Potosí and Guadalajara are 186 miles (300 km) apart.
What are the departure and arrival stations when taking the bus from San Luis Potosí to Guadalajara?
Most of the buses traveling from San Luis Potosí to Guadalajara leave from Central de Autobuses and arrive at Guadalajara Airport. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$44
11/20
$50
Today
$50
11/22
$50
11/23
$50
11/24
$50
11/25
$32
11/26
$53
The cheapest trip from San Luis Potosí to Guadalajara, MX was searched and found on Nov 25, 2025 with a price of $32
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Potosí to Guadalajara, MX, as early as possible.
You can expect to pay from $32 to $68 for a bus ticket from San Luis Potosí to Guadalajara, MX based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-11-25.
Usually ETN will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from San Luis Potosí to Guadalajara, MX was searched and found on Nov 25, 2025 with a price of $32
