Bus from Greenville, SC to New Orleans: Tickets & Schedules

Next bus departures

Next departures for Greenville to New Orleans on January 30
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
New Orleans Bus StationCheapest
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
New Orleans Bus StationFastest
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
New Orleans Bus StationNo tags
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
New Orleans Intl Airport, 900 Airline DrNo tags

Last refresh of the prices: Today at 3:28 AM EST.

Compare 2 ways to go from Greenville to New Orleans

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach New Orleans. The journey takes about 16 hours 41 minutes and with fares starting at just $134, it presents an excellent value for a comfortable ride.

1train per day
16h 41mAverage Duration
560 milesDistance
82kgCO₂ emissions
Average Price$80 - $297Average Duration19h 55m
23kg CO₂e
Average Price$134 - $282Average Duration16h 41m
82kg CO₂e

Frequently asked questions about traveling from Greenville, SC to New Orleans by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to New Orleans?

    The cheapest bus tickets from Greenville to New Orleans start from $80. The average price for this route is around $116. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to New Orleans?

    The average bus trip duration from Greenville to New Orleans is 19h 55m, covering a distance of 564 miles (910 km). The quickest bus can get you there in 13h 55m and is operated by FlixBus.

  3. Which bus companies service the Greenville to New Orleans route?

    Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Greenville to New Orleans?

    The earliest bus departs from Greenville to New Orleans at 2:45pm. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to New Orleans?

    A bus trip from Greenville to New Orleans generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Greenville to New Orleans?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to New Orleans?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Greenville to New Orleans?

    According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to New Orleans?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/26
$75
01/27
$160
Today
No data
01/29
No data
01/30
$152
01/31
$143
02/01
$112
02/02
No data
busbud logoThe cheapest trip from Greenville, SC to New Orleans was searched and found on Jan 26, 2026 with a price of $75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to New Orleans, as early as possible.

You can expect to pay from $75 to $160 for a bus ticket from Greenville, SC to New Orleans based on the last 2 days. You can expect to find the cheapest price for the trip at $112 which is on 2026-02-01.

What's the cheapest way to go from Greenville, SC to New Orleans?

busbud logoThe Bus is the cheapest travel choice for this destination

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