What is the travel distance from Gainesville to Key West?

About 354 miles (570 km) separate Gainesville and Key West.

What are the departure and arrival stations when taking the bus from Gainesville to Key West?

The majority of buses traveling from Gainesville to Key West start their journey at Rosa Parks Station and wind up at Caroline St. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.

What are the best sights and things to do in Key West?

Once in Key West, you can start exploring the city and discover its surroundings. The top sights and things to do are Ernest Hemingway House and Museum, Duval street, Key West Lighthouse & Keeper’s Quarters Museum, Fort Zachary Taylor State Park Beach and Truman Little White House.

Bus Gainesville to Key West from $71 | Refundable Tickets

Next bus departures

Next departures for Gainesville to Key West on November 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	10:40pm	Rosa Parks Station	16h 50m	3:30pm	Key West Bus Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	6:05pm	Rosa Parks Station	15h 25m	9:30am	Key West Bus Station	Fastest

Last refresh of the prices: Yesterday at 4:21 PM EST.

Get from Gainesville to Key West

This route is served by bus only

The journey takes about 15 hours 25 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.

4bus per day

15h 25mAverage Duration

353 milesDistance

14kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,384 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,380 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Gainesville and Key West?

Stops in Gainesville

A - Rosa Parks Station

B - Williston Rd & I-75

C - Greyhound Station

Stops in Key West

A - Caroline St

B - EYW Airport

Frequently asked questions about traveling from Gainesville, FL to Key West by bus

What is the travel distance from Gainesville to Key West?
What are the departure and arrival stations when taking the bus from Gainesville to Key West?
What are the best sights and things to do in Key West?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/18

$97

11/19

No data

Today

$126

11/21

No data

11/22

No data

11/23

$71

11/24

No data

11/25

No data

The cheapest trip from Gainesville, FL to Key West was searched and found on Nov 23, 2025 with a price of $71

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Key West, as early as possible.

You can expect to pay from $71 to $126 for a bus ticket from Gainesville, FL to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-11-23.