Next departures for Frankfurt am Main to Prague on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt - Main bus station
Florenc
CheapestFastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
Prague (Central Bus Station Florenc)
No tags
Bus
FRA Frankfurt airport
Prague (Na Knížecí)
No tags
Next departures for Frankfurt am Main to Prague on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Hbf
Prague (Central Bus Station Florenc)
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt central
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Next departures for Frankfurt am Main to Prague on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Hbf
Prague (Central Bus Station Florenc)
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt - Main bus station
Florenc
CheapestFastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Last refresh of the prices: Today at 5:48 PM CET.
Compare 3 ways to go from Frankfurt am Main to Prague
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Prague. The journey takes about 5 hours 20 minutes and with fares starting at just $29, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 19 reviews, the company was rated 4.2 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the timeliness. KLR Bus ticket prices on this trip start at $17
Based on 18 reviews, the company was rated 3.6 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the wifi. Racic Eurobus ticket prices on this trip start at $35
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the value for money but often complained with the wifi. RegioJet ticket prices on this trip start at $34
Based on 11143 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $30
Musil Tour offers 1 daily buses from Frankfurt am Main to Prague. Though the average price for this trip is $57, you can find tickets starting at $57. The trip between the two cities usually takes about 580.
Based on 490 reviews, the company was rated 3.9 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the power outlets. Infobus ticket prices on this trip start at $52
LEX CLUB offers 1 daily buses from Frankfurt am Main to Prague. Though the average price for this trip is $32, you can find tickets starting at $32. The trip between the two cities usually takes about 870.
Frequently asked questions about traveling from Frankfurt am Main to Prague by bus
What is the travel distance from Frankfurt am Main to Prague?
About 254 miles (410 km) separate Frankfurt am Main and Prague.
What are the departure and arrival stations when taking the bus from Frankfurt am Main to Prague?
The majority of buses traveling from Frankfurt am Main to Prague start their journey at Frankfurt Airport and wind up at PRG Airport. These are the main pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Prague?
Once in Prague, you can start exploring the city and discover its surroundings. The top sights and things to do are Mind Maze, Prague Shooting Trips, Old Town City Hall & Astronomical Clock, Casino and Staronová Synagoga (Old-New Synagogue).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$59
11/19
$16
Today
$54
11/21
$19
11/22
$32
11/23
$19
11/24
$16
11/25
$29
The cheapest trip from Frankfurt am Main to Prague was searched and found on Nov 24, 2025 with a price of $16
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Prague, as early as possible.
You can expect to pay from $16 to $96 for a bus ticket from Frankfurt am Main to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $16 which is on 2025-11-24.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Frankfurt am Main to Prague was searched and found on Nov 24, 2025 with a price of $16
