Next departures for Frankfurt am Main to Prague on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Hbf
Prague (Central Bus Station Florenc)
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt - Main bus station
Florenc
CheapestFastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Bus
FRA Frankfurt airport
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Hbf
Prague (Central Bus Station Florenc)
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Next departures for Frankfurt am Main to Prague on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt central
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Next departures for Frankfurt am Main to Prague on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Frankfurt Main Airport P36
Florenc
Cheapest
Bus
Frankfurt - Main bus station
Florenc
Fastest
Bus
Frankfurt Hbf
PRG Airport
No tags
Bus
Frankfurt Main Train Station
Florenc
No tags
Bus
Frankfurt Hbf
PRG Airport
No tags
Last refresh of the prices: Today at 6:03 AM CET.
Compare 3 ways to go from Frankfurt am Main to Prague
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 20 minutes, and with fares starting at just $41, it presents an excellent value for a comfortable ride.
Based on 11440 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $44
Based on 19 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the timeliness. KLR Bus ticket prices on this trip start at $24
Based on 18 reviews, the company was rated 3.6 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the WiFi. Racic Eurobus ticket prices on this trip start at $50
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the departure location and the value for money but often complained with the WiFi. RegioJet ticket prices on this trip start at $48
Based on 11158 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. BlaBlaCar Bus ticket prices on this trip start at $43
Musil Tour offers 1 daily buses from Frankfurt am Main to Prague. Though the average price for this trip is $82, you can find tickets starting at $82. The trip between the two cities usually takes about 580.
Based on 490 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the power outlets. Infobus ticket prices on this trip start at $75
LEX CLUB offers 1 daily buses from Frankfurt am Main to Prague. Though the average price for this trip is $47, you can find tickets starting at $46. The trip between the two cities usually takes about 870.
Frequently asked questions about travelling from Frankfurt am Main to Prague by bus
What is the travel distance from Frankfurt am Main to Prague?
The distance covered from Frankfurt am Main to Prague is 410 km (254 miles).
What are the departure and arrival locations for buses traveling from Frankfurt am Main to Prague?
Buses traveling this route start their trip at Frankfurt Airport, in Frankfurt am Main, and end it at Florenc, in Prague.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-23
$59
11-24
$53
Today
$46
11-26
$23
11-27
$45
11-28
$29
11-29
$43
11-30
$29
The cheapest trip from Frankfurt am Main to Prague was searched and found on Nov 26, 2025 with a price of $23
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Prague, as early as possible.
You can expect to pay from $23 to $159 for a bus ticket from Frankfurt am Main to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $23 which is on 2025-11-26.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Frankfurt am Main to Prague was searched and found on Nov 26, 2025 with a price of $23
