What is the travel distance from Florence to Orlando?

The distance separating Florence and Orlando is 405 miles (653 km).

What are the departure and arrival stations when taking the bus from Florence to Orlando?

The majority of buses traveling from Florence to Orlando start their journey at Florence Bus Station and wind up at Orlando Bus Station. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Orlando?

Once in Orlando, you can start exploring the city and discover its surroundings. The top sights and things to do are K1 Speed, Winter Park, Exotic Animal Experience, ESPN Wide World of Sports Complex and Hard Rock Live.

Bus Florence to Orlando from $57 | Refundable Tickets

Next bus departures

Next departures for Florence to Orlando on November 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	8h 55m	12:55am	Orlando Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	17h 55m	5:50am	Orlando Bus Station	No tags
	Bus	11:55am	Bus station	20h 50m	8:45am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	23h 15m	11:10am	Orlando Bus Station	No tags
	Bus	4:10pm	Bus station	16h 35m	8:45am	Orlando Bus Station	No tags

Next departures for Florence to Orlando on November 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	8h 55m	12:55am	Orlando Bus Station	Cheapest
	Bus	5:45am	Florence, SC	8h 25m	2:10pm	Orlando Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	17h 55m	5:50am	Orlando Bus Station	No tags
	Bus	11:55am	Bus station	20h 50m	8:45am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	23h 15m	11:10am	Orlando Bus Station	No tags

Next departures for Florence to Orlando on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	8h 55m	12:55am	Orlando Bus Station	Cheapest
	Bus	5:45am	Florence, SC	8h 25m	2:10pm	Orlando Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	17h 55m	5:50am	Orlando Bus Station	No tags
	Bus	11:55am	Bus station	20h 50m	8:45am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	23h 15m	11:10am	Orlando Bus Station	No tags

Next departures for Florence to Orlando on November 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	8h 55m	12:55am	Orlando Bus Station	Cheapest
	Bus	5:45am	Florence, SC	8h 25m	2:10pm	Orlando Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	17h 55m	5:50am	Orlando Bus Station	No tags
	Bus	11:55am	Bus station	20h 50m	8:45am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	23h 15m	11:10am	Orlando Bus Station	No tags

Next departures for Florence to Orlando on November 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	8h 55m	12:55am	Orlando Bus Station	Cheapest
	Bus	5:45am	Florence, SC	8h 25m	2:10pm	Orlando Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	17h 55m	5:50am	Orlando Bus Station	No tags
	Bus	11:55am	Bus station	20h 50m	8:45am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	23h 15m	11:10am	Orlando Bus Station	No tags

Next departures for Florence to Orlando on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	4:00pm	Bus station	8h 55m	12:55am	Orlando Bus Station	Cheapest
	Bus	5:45am	Florence, SC	8h 25m	2:10pm	Orlando Bus Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	17h 55m	5:50am	Orlando Bus Station	No tags
	Bus	11:55am	Bus station	20h 50m	8:45am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	11:55am	Bus station	23h 15m	11:10am	Orlando Bus Station	No tags

Last refresh of the prices: Yesterday at 6:30 PM EST.

Compare 2 ways to go from Florence to Orlando

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Orlando. The journey takes about 9 hours 46 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.

2train per day

9h 46mAverage Duration

403 milesDistance

59kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$58 - $196	Average Duration17h 55m	CO₂ emissions 16kg CO₂e
Train	Average Price$64 - $176	Average Duration9h 46m	CO₂ emissions 59kg CO₂e

Compare bus companies

Greyhound

3.5/587,382 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,371 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Florence and Orlando?

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Stops in Orlando

A - Orlando Bus Station

B - Orlando RedCoach Station

C - Jet Set Express Terminal

D - Disney World

E - International Dr SuperTours Terminal

F - Seaworld Hotels

Frequently asked questions about traveling from Florence, SC, US to Orlando by bus

What is the travel distance from Florence to Orlando?
What are the departure and arrival stations when taking the bus from Florence to Orlando?
What are the best sights and things to do in Orlando?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/17

$70

11/18

$68

Today

$82

11/20

$74

11/21

$82

11/22

$82

11/23

$92

11/24

$84

The cheapest trip from Florence, SC, US to Orlando was searched and found on Nov 18, 2025 with a price of $68

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Orlando, as early as possible.

You can expect to pay from $68 to $192 for a bus ticket from Florence, SC, US to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2025-11-20.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.