How much is the bus ticket from Durham to Chicago?

The cheapest bus tickets from Durham to Chicago start from $85. The average price for this route is around $194. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Durham to Chicago?

The average bus trip duration from Durham to Chicago is 1d 1h, covering a distance of 612 miles (987 km). The quickest bus can get you there in 22h 20m and is operated by FlixBus .

Which bus companies service the Durham to Chicago route?

Several major bus companies operate on this route with 13 buses available per day, including services from FlixBus , Greyhound .

What is the earliest and latest departure time for the bus from Durham to Chicago?

The earliest bus departs from Durham to Chicago at 1:10am. And the latest bus departs at 10:05pm.

What are the CO₂ emissions for the bus trip from Durham to Chicago?

A bus trip from Durham to Chicago generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Durham to Chicago?

According to Busbud customers, the highest-rated bus company on this route is FlixBus , with an average rating of 3.5 out of 5 stars based on 11380 reviews.

Which bus company has the best Wi-Fi from Durham to Chicago?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Durham to Chicago?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Durham to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Durham to Chicago from $112 | Refundable Tickets

Next bus departures

Next departures for Durham to Chicago on November 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:05pm	Durham Greyhound Bus Station	1d 1h	11:00pm	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	8:30am	Durham Greyhound Bus Station	1d	7:50am	537-517 W. Jackson Blvd	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	8:30am	Durham Greyhound Bus Station	1d	8:15am	Downtown Greyhound Station	No tags
	Bus	4:25pm	Durham Greyhound Bus Station	1d 4h	8:10pm	Downtown Greyhound Station	No tags
	Bus	10:05pm	Durham Greyhound Bus Station	1d 3h	12:10am	Downtown Greyhound Station	No tags

Next departures for Durham to Chicago on December 1
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:05pm	Durham Greyhound Bus Station	1d 1h	11:00pm	Chicago 95Th & Dan Ryan	Cheapest
	Bus	2:30am	Durham Greyhound Bus Station	22h 20m	11:50pm	Chicago 95Th & Dan Ryan	Fastest
	Bus	2:30am	Durham Greyhound Bus Station	22h 40m	12:10am	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	8:30am	Durham Greyhound Bus Station	1d	8:15am	Downtown Greyhound Station	No tags
	Bus	4:25pm	Durham Greyhound Bus Station	1d 4h	8:10pm	Downtown Greyhound Station	No tags

Last refresh of the prices: Today at 12:10 PM EST.

Compare 2 ways to go from Durham to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 1 hour 55 minutes and with fares starting at just $85, it presents an excellent value for a comfortable ride.

13bus per day

1d 1hAverage Duration

612 milesDistance

25kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$85 - $405	Average Duration1d 1h	CO₂ emissions 25kg CO₂e
Train	Average Price$211 - $1,824	Average Duration1d 15h	CO₂ emissions 91kg CO₂e

Where are the popular stops in Durham and Chicago?

Stops in Durham

A
Durham Greyhound Bus Station
515 W Pettigrew St , Durham, NC 27703
Visit page
B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA
C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA
D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

FlixBus

3.5/511,475 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,408 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Durham, NC, US to Chicago by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Durham to Chicago?
The cheapest bus tickets from Durham to Chicago start from $85. The average price for this route is around $194. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Chicago?
The average bus trip duration from Durham to Chicago is 1d 1h, covering a distance of 612 miles (987 km). The quickest bus can get you there in 22h 20m and is operated by FlixBus.
Which bus companies service the Durham to Chicago route?
Several major bus companies operate on this route with 13 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Durham to Chicago?
The earliest bus departs from Durham to Chicago at 1:10am. And the latest bus departs at 10:05pm.
What are the CO₂ emissions for the bus trip from Durham to Chicago?
A bus trip from Durham to Chicago generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Durham to Chicago?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Durham to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Durham to Chicago?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Durham to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/27

$200

11/28

$220

Today

$325

11/30

$291

12/01

$181

12/02

No data

12/03

No data

12/04

No data

The cheapest trip from Durham, NC, US to Chicago was searched and found on Dec 1, 2025 with a price of $181

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Chicago, as early as possible.

You can expect to pay from $181 to $583 for a bus ticket from Durham, NC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $181 which is on 2025-12-01.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.