Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Sur | Melipeuco | CheapestFastest | ||||
| Bus | Terminal Sur | Melipeuco | No tags |
Last refresh of the prices: Yesterday at 11:01 AM -03.
Get from Santiago to Melipeuco
The journey takes about 10 hours, and with fares starting at just R 217, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santiago and Melipeuco?
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Zapadores
Los Zapadores 608, Recoleta, Región Metropolitana, Chile
Stops in Melipeuco
- A
Terminal Melipeuco
Pincheira, Melipeuco, IX Región, Chile
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Frequently asked questions about travelling from Santiago, CL to Melipeuco by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Santiago to Melipeuco?
The cheapest bus tickets from Santiago to Melipeuco start at R 217. The average price for this route is around R 443. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Santiago to Melipeuco?
The average bus journey time from Santiago to Melipeuco is 10h, covering a distance of 607 km. The fastest bus gets you there in 9h 45m and is operated by buses TranSantin.
Which bus companies service the Santiago to Melipeuco route?
Several major bus companies operate on this route with 3 buses available per day, including services from Nar Bus, buses TranSantin.
What is the earliest and latest departure time for the bus from Santiago to Melipeuco?
The earliest bus departs from Santiago to Melipeuco at 22:00. And the latest bus departs at 22:45.
What are the CO₂ emissions for the bus trip from Santiago to Melipeuco?
A bus trip from Santiago to Melipeuco produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Santiago to Melipeuco?
According to Busbud customers, the highest-rated bus company on this route is buses TranSantin, with an average rating of 4.1 out of 5 stars based on 289 reviews.
Which bus company has the best Wi-Fi from Santiago to Melipeuco?
Based on reviews on Busbud, the bus company Nar Bus has the best Wi-Fi rating with a score of 3.0.
Which bus company offers the most punctual service from Santiago to Melipeuco?
According to Busbud traveller reviews, the most punctual bus company on this route is buses TranSantin, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Santiago to Melipeuco?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is buses TranSantin, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago, CL to Melipeuco was searched and found on 25 Dec 2025 with a price of R 575To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to Melipeuco as early as possible.
You can expect to pay from R 575 to R 652 for a bus ticket from Santiago, CL to Melipeuco based on the last 2 days. You can expect to find the cheapest price for the trip at R 619, which is on 2025-12-31.
