Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Milan (Assago M2) | Terminal Interbus | No tags | ||||
| Bus | Milan (Malpensa Aeroporto Terminal 1) | Terminal Interbus | No tags | ||||
| Bus | Aeroporto Malpensa T2 | Terminal Interbus | No tags | ||||
| Bus | Lampugnano bus station | Terminal Interbus | No tags | ||||
| Bus | Milan (San Donato M3) | Terminal Interbus | No tags |
Compare 3 ways to travel from Milano to Syracuse
Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just R 1 010, it presents an excellent value for a comfortable ride.
Where are the popular stops in Milano and Syracuse?
Stops in Milano
- APiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- BVia Giulio Natta, 228, 20151 Milano, Italy
- C
Linate Airport
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Syracuse
- AViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Compare bus companies
Based on 11446 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 1 010
Frequently asked questions about travelling from Milano to Syracuse by bus
How much does a bus ticket from Milano to Syracuse cost?
The bus ticket price from Milano to Syracuse starts at R 1 010. The best way to find cheap bus tickets from Milano to Syracuse is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Milano to Syracuse?
The average travel time between Milano and Syracuse is around 1d 3h, although the fastest bus will take about 20h 40m. This is the time it takes to travel the 1064 km that separates the two cities.
How many daily bus connections are there between Milano and Syracuse?
The number of buses from Milano to Syracuse can differ depending on the day of the week. On average, there are 6 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Milano to Syracuse by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Milano to Syracuse?
When taking the bus from Milano to Syracuse, you can travel comfortably and safely with FlixBus.
What are the departure and arrival stations when taking the bus from Milano to Syracuse?
Buses travelling between Milano and Syracuse leave from Piazza I Maggio, 1 or Lampugnano and arrive at Fermata dell'autobus Siracusa, Siracusa, Siracusa - Terminal Bus (Stazione FS).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Syracuse was searched and found on 24 Nov 2025 with a price of R 944To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Syracuse as early as possible.
You can expect to pay from R 944 to R 1 819 for a bus ticket from Milano to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 061, which is on 2025-12-01.
What's the cheapest way to go from Milano to Syracuse?
The bus is the cheapest travel choice for this destination
