Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Milan (Assago M2) | Terminal Interbus | No tags | ||||
| Bus | Milan (Malpensa Aeroporto Terminal 1) | Terminal Interbus | No tags | ||||
| Bus | Aeroporto Malpensa T2 | Terminal Interbus | No tags | ||||
| Bus | Lampugnano bus station | Terminal Interbus | No tags | ||||
| Bus | Milan (San Donato M3) | Terminal Interbus | No tags |
Compare 3 ways to travel from Milano to Syracuse
Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just £45, it presents an excellent value for a comfortable ride.
Where are the popular stops in Milano and Syracuse?
Stops in Milano
- APiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- BVia Giulio Natta, 228, 20151 Milano, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Syracuse
- AViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Compare bus companies
Based on 11448 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £45
Frequently asked questions about travelling by bus from Milano to Syracuse
How far is Syracuse from Milano by coach?
The journey from Milano to Syracuse by coach covers an approximate distance of 660 miles (1064 km).
Is there a way to reach Syracuse from Milano without flying?
To travel from Milano to Syracuse without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Syracuse was searched and found on 24 Nov 2025 with a price of £42To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Syracuse as early as possible.
You can expect to pay from £42 to £81 for a bus ticket from Milano to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at £47, which is on 2025-12-01.
What's the cheapest way to go from Milano to Syracuse?
The bus is the cheapest travel choice for this destination
