Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal Rodoviario de Iquique | Terminal San Borja | Cheapest | |||||
 | Terminal Rodoviario Iquique | San Borja | Fastest | |||||
 | Terminal Rodoviario De Iquique, Calle Patricio Lynch #50 | Terminal de Buses San Borja - San Francisco de Borja | No tags | |||||
 | Terminal Rodoviario De Iquique, Calle Patricio Lynch #50 | San Borja | No tags | |||||
| Terminal Rodoviario Iquique | San Borja | No tags |
Last refresh of the prices: Today at 10:14 AM -03.
Accepted payments
Get from Iquique to Santiago
The journey takes about 1 day, 1 hour, and with fares starting at just US$34, it presents an excellent value for a comfortable ride.
Bus Iquique to Santiago, CL: Trip Overview
Compare bus companies
Iquique to Santiago Bus
With Busbud, comparing and booking tickets for a bus from Iquique to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Iquique to Santiago from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Santiago from Iquique, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Iquique and Santiago?
Frequently asked questions on the trip Iquique - Santiago, CL
How much does a bus ticket from Iquique to Santiago cost?
The bus ticket price from Iquique to Santiago starts at US$34. The best way to find cheap bus tickets from Iquique to Santiago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Iquique to Santiago?
The average travel time between Iquique and Santiago is around 1d 1h, although the fastest bus will take about 23h 15m. This is the time it takes to travel the 1472 km that separates the two cities.
How many daily bus connections are there between Iquique and Santiago?
The number of buses from Iquique to Santiago can differ depending on the day of the week. On average, there are 22 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Iquique to Santiago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Iquique to Santiago?
When taking the bus from Iquique to Santiago, you can travel comfortably and safely with Pullman San Andres, Cikbus Elité, Pluss Chile.
What are the departure and arrival stations when taking the bus from Iquique to Santiago?
Buses travelling between Iquique and Santiago leave from Patricio Lynch 60 or Guatacondo 3430 and arrive at San Borja, Terminal Sur, Terminal Los Héroes.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Iquique to Santiago, CL was searched and found on 03 Nov 2025 with a price of US$41To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Iquique to Santiago, CL as early as possible.
You can expect to pay from US$41 to US$69 for a bus ticket from Iquique to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at US$41, which is on 2025-11-07.
Usually Cikbus Elité, Pullman San Andres will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Iquique to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Iquique to Santiago, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Iquique to Santiago.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Iquique to Santiago.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Iquique
Buses Leaving from Iquique
- Bus from Iquique to Antofagasta
- Coach Iquique - Santiago
- Bus Iquique - Calama
- Bus from Iquique to Alto Hospicio
- Coach Iquique - Cochabamba
- Bus Iquique - Puerto Montt
- Bus from Iquique to Tocopilla
- Coach Iquique - Los Vilos
- Bus Iquique - Vallenar
- Bus from Iquique to Sierra Gorda
- Coach Iquique - Quillota
- Bus Iquique - Valdivia
- Bus from Iquique to Pichidangui
- Coach Iquique - Caldera
- Bus Iquique - Copiapo
Buses Going to Iquique
- Bus from Santiago to Iquique
- Coach Calama - Iquique
- Bus Copiapo - Iquique
- Bus from La Paz to Iquique
- Coach Coquimbo - Iquique
- Bus Temuco - Iquique
- Bus from Llaillay to Iquique
- Coach Vina del Mar - Iquique
- Bus Taltal - Iquique
- Bus from Antofagasta to Iquique
- Coach Valdivia - Iquique
- Bus Sierra Gorda - Iquique
- Bus from Arica Province to Iquique
- Coach Puerto Montt - Iquique
- Bus Tocopilla - Iquique
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Puerto Montt
- Coach Santiago - Concepción
- Bus Santiago - Antofagasta
- Bus from Santiago to Mendoza
- Coach Santiago - La Serena
- Bus Santiago - Temuco
- Bus from Santiago to Los Alamos
- Coach Santiago - La Boca
- Bus Santiago - Licanray
- Bus from Santiago to Laraquete
- Coach Santiago - Carahue
- Bus Santiago - Quintero
- Bus from Santiago to Valparaiso
- Coach Santiago - Cholchol
- Bus Santiago - Coronel
Buses Going to Santiago
- Bus from Victoria to Santiago
- Coach Concepción - Santiago
- Bus Mendoza - Santiago
- Bus from Castro to Santiago
- Coach Valdivia - Santiago
- Bus Antofagasta - Santiago
- Bus from Labranza to Santiago
- Coach Pupuya - Santiago
- Bus La Boca - Santiago
- Bus from Alto Hospicio to Santiago
- Coach Vicuña - Santiago
- Bus Matanzas - Santiago
- Bus from Los Lagos to Santiago
- Coach Casablanca - Santiago
- Bus Purén - Santiago