Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Indianapolis Bus Station | Knoxville Bus Station | CheapestFastest |
Last refresh of the prices: Yesterday at 9:13 AM EST.
Get from Indianapolis to Knoxville
The journey takes about 10 hours 20 minutes, and with fares starting at just R 1 244, it presents an excellent value for a comfortable ride.
Where are the popular stops in Indianapolis and Knoxville?
Stops in Indianapolis
- A350 S Illinois St, Indianapolis, IN 46225
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87512 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 244
Frequently asked questions about travelling from Indianapolis to Knoxville, TN by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Indianapolis to Knoxville?
The cheapest bus tickets from Indianapolis to Knoxville start at R 1 244. The average price for this route is around R 1 979. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Indianapolis to Knoxville?
The average bus journey time from Indianapolis to Knoxville is 10h 20m, covering a distance of 464 km. The fastest bus gets you there in 9h 45m and is operated by Greyhound.
Which bus companies service the Indianapolis to Knoxville route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Indianapolis to Knoxville?
The earliest bus departs from Indianapolis to Knoxville at 09:10. And the latest bus departs at 11:25.
What are the CO₂ emissions for the bus trip from Indianapolis to Knoxville?
A bus trip from Indianapolis to Knoxville produces an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Knoxville, TN was searched and found on 19 Jan 2026 with a price of R 1 621To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Knoxville, TN as early as possible.
