Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Downtown Transit Center | Knoxville Bus Station | No tags | ||||
 | Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Downtown Transit Center | Knoxville Bus Station | No tags | ||||
| Bus | Indianapolis Bus Station | Knoxville Bus Station | No tags |
Get from Indianapolis to Knoxville
The journey takes about 11 hours 15 minutes, and with fares starting at just R 1 239, it presents an excellent value for a comfortable ride.
Where are the popular stops in Indianapolis and Knoxville?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Frequently asked questions about travelling from Indianapolis to Knoxville, TN by bus
How much does a bus ticket from Indianapolis to Knoxville cost?
The bus ticket price from Indianapolis to Knoxville starts at R 1 239. The best way to find cheap bus tickets from Indianapolis to Knoxville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Indianapolis to Knoxville?
The average travel time between Indianapolis and Knoxville is around 11h 15m, although the fastest bus will take about 9h 45m. This is the time it takes to travel the 468 km that separates the two cities.
How many daily bus connections are there between Indianapolis and Knoxville?
The number of buses from Indianapolis to Knoxville can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Indianapolis to Knoxville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Indianapolis to Knoxville?
When taking the bus from Indianapolis to Knoxville, you can travel comfortably and safely with Greyhound, FlixBus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Knoxville, TN was searched and found on 19 Nov 2025 with a price of R 1 112To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Knoxville, TN as early as possible.
You can expect to pay from R 1 112 to R 3 196 for a bus ticket from Indianapolis to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 748, which is on 2025-11-23.
