Bus from Indianapolis to Knoxville, TN: Tickets & Schedules

Previously seen trips

Next departures for Indianapolis to Knoxville on November 27
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
Indianapolis Bus Station
Knoxville Bus StationNo tags
FlixBus + Greyhound
Bus
Downtown Transit Center
Knoxville Bus StationNo tags
GreyhoundBus
Indianapolis Bus Station
Knoxville Bus StationNo tags
GreyhoundBus
Indianapolis Bus Station
Knoxville Bus StationNo tags
GreyhoundBus
Indianapolis Bus Station
Knoxville Bus StationNo tags

Get from Indianapolis to Knoxville

This route is served by bus only

The journey takes about 11 hours 15 minutes, and with fares starting at just $101, it presents an excellent value for a comfortable ride.

2bus per day
11h 15mAverage Duration
464 kmDistance
12kgCO₂ emissions

Frequently asked questions about travelling from Indianapolis to Knoxville, TN by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Indianapolis to Knoxville?

    The cheapest bus tickets from Indianapolis to Knoxville start from $101. The average price for this route is around $159. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Indianapolis to Knoxville?

    The average bus travel time from Indianapolis to Knoxville is 11h 15m, covering a distance of 464 km. The quickest bus can get you there in 9h 45m and is operated by Greyhound.

  3. Which bus companies service the Indianapolis to Knoxville route?

    Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, FlixBus.

  4. What are the earliest and latest departure times for the bus from Indianapolis to Knoxville?

    The earliest bus departs from Indianapolis to Knoxville at 9:10am. And the latest bus departs at 11:30pm.

  5. What are the CO₂ emissions for the bus trip from Indianapolis to Knoxville?

    A bus trip from Indianapolis to Knoxville generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Indianapolis to Knoxville?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.

  7. Which bus company has the best Wi-Fi from Indianapolis to Knoxville?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Indianapolis to Knoxville?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Indianapolis to Knoxville?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-25
$226
11-26
$208
Today
No data
11-28
No data
11-29
No data
11-30
No data
12-01
No data
12-02
No data
busbud logoThe cheapest trip from Indianapolis to Knoxville, TN was searched and found on Nov 26, 2025 with a price of $208

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Knoxville, TN, as early as possible.

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