Bus from Harrisburg to Greenville, SC: Tickets & Timetables

Previously seen journeys

Next departures from Harrisburg to Greenville on 26 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
FlixBus + Greyhound
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
FlixBus + Greyhound
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags

Compare 2 ways to travel from Harrisburg to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 16 hours 19 minutes and with fares starting at just R 2 894, it presents an excellent value for a comfortable ride.

1train per day
16h 19mAverage duration
774 kmDistance
70kgCO₂ emissions
Average priceR 1 224 - R 6 501Average duration22h 45m
19kg CO₂e
Average priceR 2 894 - R 11 873Average duration16h 19m
70kg CO₂e

Frequently asked questions about travelling from Harrisburg to Greenville, SC by bus

  1. How much does a bus ticket from Harrisburg to Greenville cost?

    The bus ticket price from Harrisburg to Greenville starts at R 1 224. The best way to find cheap bus tickets from Harrisburg to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Harrisburg to Greenville?

    The average travel time between Harrisburg and Greenville is around 22h 45m, although the fastest bus will take about 20h 5m. This is the time it takes to travel the 775 km that separates the two cities.

  3. How many daily bus connections are there between Harrisburg and Greenville?

    The number of buses from Harrisburg to Greenville can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Harrisburg to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Harrisburg to Greenville?

    When taking the bus from Harrisburg to Greenville, you can travel comfortably and safely with Greyhound, FlixBus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/11
No data
25/11
No data
Today
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27/11
No data
28/11
No data
29/11
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30/11
R 3 758
01/12
No data
busbud logoThe cheapest trip from Harrisburg to Greenville, SC was searched and found on 30 Nov 2025 with a price of R 3 758

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Greenville, SC as early as possible.

You can expect to pay from R 3 758 to R 3 758 for a bus ticket from Harrisburg to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 3 758, which is on 2025-11-30.

What's the cheapest way to go from Harrisburg to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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