Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Harrisburg Bus Station | 1116 Woodruff Rd | No tags | ||||
FlixBus + Greyhound | Bus | Harrisburg Bus Station | 1116 Woodruff Rd | No tags | ||||
FlixBus + Greyhound | Bus | Harrisburg Bus Station | 1116 Woodruff Rd | No tags | ||||
Greyhound + FlixBus | Bus | Harrisburg Bus Station | 1116 Woodruff Rd | No tags | ||||
Greyhound + FlixBus | Bus | Harrisburg Bus Station | 1116 Woodruff Rd | No tags |
Compare 2 ways to travel from Harrisburg to Greenville
Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 16 hours 19 minutes and with fares starting at just £129, it presents an excellent value for a comfortable ride.
Where are the popular stops in Harrisburg and Greenville?
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Compare bus companies
Frequently asked questions about travelling by bus from Harrisburg to Greenville, SC
What's the distance between Harrisburg and Greenville by coach?
The journey from Harrisburg to Greenville by coach covers an approximate distance of 481 miles (775 km).
How can I travel from Harrisburg to Greenville avoiding air travel?
To travel from Harrisburg to Greenville without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to Greenville, SC was searched and found on 30 Nov 2025 with a price of £167To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Greenville, SC as early as possible.
You can expect to pay from £167 to £167 for a bus ticket from Harrisburg to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £167, which is on 2025-11-30.
What's the cheapest way to go from Harrisburg to Greenville, SC?
The bus is the cheapest travel choice for this destination
