Bus from Harrisburg to Greenville, SC: Tickets & Timetables

Previously seen journeys

Next departures from Harrisburg to Greenville on 26 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
FlixBus + Greyhound
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
FlixBus + Greyhound
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags
Greyhound + FlixBus
Bus
Harrisburg Bus Station
1116 Woodruff RdNo tags

Compare 2 ways to travel from Harrisburg to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 16 hours 19 minutes and with fares starting at just £129, it presents an excellent value for a comfortable ride.

1train per day
16h 19mAverage duration
480 milesDistance
70kgCO₂ emissions
Average price£55 - £289Average duration22h 45m
19kg CO₂e
Average price£129 - £527Average duration16h 19m
70kg CO₂e

Frequently asked questions about travelling by bus from Harrisburg to Greenville, SC

  1. What's the distance between Harrisburg and Greenville by coach?

    The journey from Harrisburg to Greenville by coach covers an approximate distance of 481 miles (775 km).

  2. How can I travel from Harrisburg to Greenville avoiding air travel?

    To travel from Harrisburg to Greenville without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/11
No data
25/11
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Today
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27/11
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28/11
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29/11
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30/11
£167
01/12
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busbud logoThe cheapest trip from Harrisburg to Greenville, SC was searched and found on 30 Nov 2025 with a price of £167

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Greenville, SC as early as possible.

You can expect to pay from £167 to £167 for a bus ticket from Harrisburg to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £167, which is on 2025-11-30.

What's the cheapest way to go from Harrisburg to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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