Train from Harrisburg to Greenville, SC: Tickets & Schedules

Previously seen trips

Next departures for Harrisburg to Greenville on November 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags
AmtrakTrain
Harrisburg, PA
Greenville StationNo tags

Compare 2 ways to go from Harrisburg to Greenville

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Greenville. The journey takes about 16 hours 19 minutes, and with fares starting at just $238, it presents an excellent value for a comfortable ride.

1train per day
16h 19mAverage Duration
774 kmDistance
70kgCO₂ emissions
Average Price$101 - $535Average Duration22h 45m
19kg CO₂e
Average Price$238 - $977Average Duration16h 19m
70kg CO₂e

Frequently asked questions about travelling from Harrisburg to Greenville, SC by train

  1. How much does a cheap train ticket from Harrisburg to Greenville cost?

    The average train ticket price from Harrisburg to Greenville is $324. The best way to find cheap train tickets from Harrisburg to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the trip from Harrisburg to Greenville?

    A train trip between Harrisburg and Greenville is around 16h 19m, although the fastest train will take about 16h 19m. This is the time it takes to travel the 775 km that separates the two cities.

  3. How many daily trains are there between Harrisburg and Greenville?

    The number of trains from Harrisburg to Greenville can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Harrisburg to Greenville by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. Which train companies travel from Harrisburg to Greenville?

    When taking the train from Harrisburg to Greenville, you can travel comfortably and safely with Amtrak.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-24
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11-25
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Today
$942
11-27
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11-28
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11-29
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11-30
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12-01
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busbud logoThe cheapest trip from Harrisburg to Greenville, SC was searched and found on Nov 26, 2025 with a price of $942

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Harrisburg to Greenville, SC, as early as possible.

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