Train from Buffalo, NY to Florence, SC, US: Tickets & Schedules

Previously seen trips

Next departures for Buffalo to Florence on December 12
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Exchange Street Station
Florence StationNo tags
AmtrakTrain
Depew Station
Florence StationNo tags
AmtrakTrain
Exchange Street Station
Florence StationNo tags
AmtrakTrain
Depew Station
Florence StationNo tags
AmtrakTrain
Exchange Street Station
Florence StationNo tags

Compare 2 ways to go from Buffalo to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 22 hours 25 minutes, and with fares starting at just $432, it presents an excellent value for a comfortable ride.

2train per day
22h 25mAverage Duration
973 kmDistance
88kgCO₂ emissions
Average Price$457 - $605Average Duration1d 6h
24kg CO₂e
Average Price$432 - $439Average Duration22h 25m
88kg CO₂e

Frequently asked questions about travelling from Buffalo, NY to Florence, SC, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Buffalo to Florence?

    The cheapest train tickets from Buffalo to Florence start at $432. The average price for this train route is around $432. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

  2. How long is the train ride from Buffalo to Florence?

    The average train trip from Buffalo to Florence takes 22h 25m and covers 973 km. The quickest train gets you there in 22h 25m and is operated by Amtrak.

  3. Which train operators serve the Buffalo to Florence route?

    Several major train operators serve this route, with 2 trains available per day.

  4. What are the earliest and latest departure times for the train from Buffalo to Florence?

    The earliest train from Buffalo to Florence departs at 4:28am. The latest train departs at 4:45am.

What's the cheapest way to go from Buffalo, NY to Florence, SC, US?

busbud logoThe train is the cheapest travel choice for this destination

The best way to travel between Buffalo, NY and Florence, SC, US is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $432 on average. If you're on a budget, you'll find cheap tickets from $432. If you're looking for the fastest way to get to Florence, SC, US, choose the train, as it will take you from Buffalo, NY to Florence, SC, US in about 22h 25m —that's the fastest way to get there!

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