- Buffalo to Florence trains
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Train | Exchange Street Station | Florence Station | No tags | ||||
![]() | Train | Depew Station | Florence Station | No tags | ||||
![]() | Train | Exchange Street Station | Florence Station | No tags | ||||
![]() | Train | Depew Station | Florence Station | No tags | ||||
![]() | Train | Exchange Street Station | Florence Station | No tags |
Compare 2 ways to go from Buffalo to Florence
Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 22 hours 25 minutes and with fares starting at just $306, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5638 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $306
Frequently asked questions about traveling from Buffalo, NY to Florence, SC, US by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Buffalo to Florence?
The cheapest train tickets from Buffalo to Florence start from $306. The average price for this train route is around $306. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Buffalo to Florence?
The average train ride duration from Buffalo to Florence is 22h 25m, covering a distance of 603 miles (973 km). The quickest train can get you there in 22h 25m and is operated by Amtrak.
Which train operators service the Buffalo to Florence route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the train from Buffalo to Florence?
The earliest train departs from Buffalo to Florence at 4:28am. And the latest train departs at 4:45am.
What's the cheapest way to go from Buffalo, NY to Florence, SC, US?
The best way to travel between Buffalo, NY and Florence, SC, US is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $306 on average. If you're on a budget, you'll find cheap tickets from $306. If you're looking for the fastest way to get to Florence, SC, US, choose the train, as it will take you from Buffalo, NY to Florence, SC, US in about 22h 25m - that's the fastest way to get there!






