Train from Buffalo, NY to Florence, SC, US: Tickets & Schedules

Previously seen trips

Next departures for Buffalo to Florence on December 12
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Exchange Street Station
Florence StationNo tags
AmtrakTrain
Depew Station
Florence StationNo tags
AmtrakTrain
Exchange Street Station
Florence StationNo tags
AmtrakTrain
Depew Station
Florence StationNo tags
AmtrakTrain
Exchange Street Station
Florence StationNo tags

Compare 2 ways to go from Buffalo to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 22 hours 25 minutes and with fares starting at just $306, it presents an excellent value for a comfortable ride.

2train per day
22h 25mAverage Duration
603 milesDistance
88kgCO₂ emissions
Average Price$324 - $429Average Duration1d 6h
24kg CO₂e
Average Price$306 - $311Average Duration22h 25m
88kg CO₂e

Frequently asked questions about traveling from Buffalo, NY to Florence, SC, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Buffalo to Florence?

    The cheapest train tickets from Buffalo to Florence start from $306. The average price for this train route is around $306. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the train journey from Buffalo to Florence?

    The average train ride duration from Buffalo to Florence is 22h 25m, covering a distance of 603 miles (973 km). The quickest train can get you there in 22h 25m and is operated by Amtrak.

  3. Which train operators service the Buffalo to Florence route?

    Several major train operators operate on this route with 2 trains available per day.

  4. What is the earliest and latest departure time for the train from Buffalo to Florence?

    The earliest train departs from Buffalo to Florence at 4:28am. And the latest train departs at 4:45am.

What's the cheapest way to go from Buffalo, NY to Florence, SC, US?

busbud logoThe train is the cheapest travel choice for this destination

The best way to travel between Buffalo, NY and Florence, SC, US is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $306 on average. If you're on a budget, you'll find cheap tickets from $306. If you're looking for the fastest way to get to Florence, SC, US, choose the train, as it will take you from Buffalo, NY to Florence, SC, US in about 22h 25m - that's the fastest way to get there!

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