Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Winston Salem Greyhound Bus Station | Boston (South Station) | Cheapest | |||||
| Winston Salem Greyhound Bus Station | Boston (South Station) | Fastest | |||||
| Winston Salem Greyhound Bus Station | Boston (South Station) | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Winston Salem Greyhound Bus Station | Brookline | No tags |
Last refresh of the prices: Yesterday at 6:47 AM EST.
Get from Winston-Salem to Boston
The journey takes about 22 hours 35 minutes, and with fares starting at just $191, it presents an excellent value for a comfortable ride.
Where are the popular stops in Winston-Salem and Boston?
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
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Frequently asked questions about travelling from Winston-Salem to Boston, MA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Winston-Salem to Boston?
The cheapest bus tickets from Winston-Salem to Boston start from $191. The average price for this route is around $290. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Winston-Salem to Boston?
The average bus travel time from Winston-Salem to Boston is 22h 35m, covering a distance of 1048 km. The quickest bus can get you there in 20h 30m and is operated by Greyhound.
Which bus companies service the Winston-Salem to Boston route?
What are the earliest and latest departure times for the bus from Winston-Salem to Boston?
The earliest bus departs from Winston-Salem to Boston at 6:10am. And the latest bus departs at 6:15pm.
What are the CO₂ emissions for the bus trip from Winston-Salem to Boston?
A bus trip from Winston-Salem to Boston generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Winston-Salem to Boston?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Winston-Salem to Boston?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Winston-Salem to Boston?
According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Winston-Salem to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Winston-Salem to Boston, MA, US was searched and found on Dec 5, 2025 with a price of $173To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Boston, MA, US, as early as possible.
You can expect to pay from $173 to $587 for a bus ticket from Winston-Salem to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $173 which is on 2025-12-05.
