How much is the bus ticket from Winston-Salem to Boston?

The cheapest bus tickets from Winston-Salem to Boston start from $133. The average price for this route is around $203. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Winston-Salem to Boston?

The average bus trip duration from Winston-Salem to Boston is 22h 35m, covering a distance of 650 miles (1048 km). The quickest bus can get you there in 20h 30m and is operated by Greyhound .

Which bus companies service the Winston-Salem to Boston route?

Several major bus companies operate on this route with 8 buses available per day, including services from Amtrak , Greyhound .

What is the earliest and latest departure time for the bus from Winston-Salem to Boston?

The earliest bus departs from Winston-Salem to Boston at 6:10am. And the latest bus departs at 6:15pm.

What are the CO₂ emissions for the bus trip from Winston-Salem to Boston?

A bus trip from Winston-Salem to Boston generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Winston-Salem to Boston?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5597 reviews.

Which bus company has the best Wi-Fi from Winston-Salem to Boston?

Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company has the most timely service from Winston-Salem to Boston?

According to Busbud traveller reviews, the most timely bus company on this route is Amtrak , with a punctuality rating of 3.8 out of 5 stars.

Which bus company has the cleanest buses from Winston-Salem to Boston?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus Winston-Salem to Boston from $120 | Refundable Tickets

Next departures

Next departures for Winston-Salem to Boston on December 1
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:15pm	Winston Salem Greyhound Bus Station	1d 1h	8:00pm	Boston (South Station)	Cheapest
	2:55pm	Winston Salem Greyhound Bus Station	20h 30m	11:25am	Boston (South Station)	Fastest
	6:17am	Winston-Salem (State University), NC	1d 3h	9:58am	Back Bay Station	No tags
	7:10am	Winston Salem Greyhound Bus Station	22h	5:10am	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	7:10am	Winston Salem Greyhound Bus Station	22h 30m	5:40am	Brookline	No tags

Next departures for Winston-Salem to Boston on December 2
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:15pm	Winston Salem Greyhound Bus Station	1d 1h	8:00pm	Boston (South Station)	Cheapest
	2:55pm	Winston Salem Greyhound Bus Station	20h 30m	11:25am	Boston (South Station)	Fastest
	6:17am	Winston-Salem (State University), NC	1d 3h	9:58am	Back Bay Station	No tags
	7:10am	Winston Salem Greyhound Bus Station	22h	5:10am	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	7:10am	Winston Salem Greyhound Bus Station	22h 30m	5:40am	Brookline	No tags

Next departures for Winston-Salem to Boston on December 5
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	7:10am	Winston Salem Greyhound Bus Station	22h 30m	5:40am	Brookline	Cheapest
Greyhound Lines, Inc. + FlixBus	2:55pm	Winston Salem Greyhound Bus Station	20h 20m	11:15am	Boston (South Station)	Fastest
	6:17am	Winston-Salem (State University), NC	1d 3h	9:58am	Back Bay Station	No tags
	7:10am	Winston Salem Greyhound Bus Station	22h	5:10am	Boston (South Station)	No tags
Greyhound Lines, Inc. + FlixBus	10:25am	Winston Salem Greyhound Bus Station	23h	9:25am	Boston (South Station)	No tags

Last refresh of the prices: Today at 10:18 AM EST.

Get from Winston-Salem to Boston

This route is served by bus only

The journey takes about 22 hours 35 minutes and with fares starting at just $133, it presents an excellent value for a comfortable ride.

8bus per day

22h 35mAverage Duration

650 milesDistance

26kgCO₂ emissions

Where are the popular stops in Winston-Salem and Boston?

Stops in Winston-Salem

A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101
Visit page
B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA
C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA
D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Compare bus companies

Amtrak

4/55,618 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Greyhound

3.5/587,410 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Winston-Salem to Boston, MA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Winston-Salem to Boston?
The cheapest bus tickets from Winston-Salem to Boston start from $133. The average price for this route is around $203. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Winston-Salem to Boston?
The average bus trip duration from Winston-Salem to Boston is 22h 35m, covering a distance of 650 miles (1048 km). The quickest bus can get you there in 20h 30m and is operated by Greyhound.
Which bus companies service the Winston-Salem to Boston route?
Several major bus companies operate on this route with 8 buses available per day, including services from Amtrak, Greyhound.
What is the earliest and latest departure time for the bus from Winston-Salem to Boston?
The earliest bus departs from Winston-Salem to Boston at 6:10am. And the latest bus departs at 6:15pm.
What are the CO₂ emissions for the bus trip from Winston-Salem to Boston?
A bus trip from Winston-Salem to Boston generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Winston-Salem to Boston?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Winston-Salem to Boston?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Winston-Salem to Boston?
According to Busbud traveller reviews, the most timely bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Winston-Salem to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/28

No data

11/29

No data

Today

No data

12/01

$225

12/02

$123

12/03

No data

12/04

No data

12/05

$120

The cheapest trip from Winston-Salem to Boston, MA, US was searched and found on Dec 5, 2025 with a price of $120

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Boston, MA, US, as early as possible.

You can expect to pay from $120 to $688 for a bus ticket from Winston-Salem to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-12-05.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.