Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | City of Portland | Baltimore Downtown Bus Station | Cheapest | |||||
Amtrak + Amtrak Acela | Portland Transportation Center | Penn Station | Fastest | |||||
 | Portland Transportation Center | Penn Station | No tags | |||||
Amtrak + Amtrak Acela | Portland Transportation Center | Penn Station | No tags | |||||
 | City of Portland | Baltimore Bus Stop | No tags |
Last refresh of the prices: Yesterday at 11:54 AM EST.
Compare 2 ways to go from Portland to Baltimore
Among the sustainable travel choices, the bus stands out as a good way to reach Baltimore. The journey takes about 15 hours 15 minutes, and with fares starting at just $82, it presents an excellent value for a comfortable ride.
Where are the popular stops in Portland and Baltimore?
Stops in Portland
- A
Greyhound Station Portland Maine
389 Congress St, Portland, ME 04102, USA
Stops in Baltimore
- A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States - B7 St Paul St, Baltimore, MD 21201, USA
- D1578 Maryland Ave, Baltimore, MD 21201, USA
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Frequently asked questions about travelling from Portland, ME to Baltimore by bus
What is the distance between Portland and Baltimore?
The distance between Portland and Baltimore is around 720 km (446 miles).
What are the departure and arrival locations for buses traveling from Portland to Baltimore?
Buses traveling this route start their trip at Greyhound Station Portland Maine, in Portland, and end it at Baltimore Downtown Bus Station, in Baltimore.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Portland, ME to Baltimore was searched and found on Nov 29, 2025 with a price of $140To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, ME to Baltimore, as early as possible.
You can expect to pay from $140 to $1,462 for a bus ticket from Portland, ME to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at $140 which is on 2025-11-29.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Portland, ME to Baltimore?
The bus is the cheapest travel choice for this destination
