Next departures for Portland to Baltimore on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
City of Portland
Baltimore Bus Stop
Cheapest
Amtrak + Amtrak Acela
Portland Transportation Center
Penn Station
Fastest
Portland Transportation Center
Penn Station
No tags
Amtrak + Amtrak Acela
Portland Transportation Center
Penn Station
No tags
City of Portland
Baltimore Downtown Bus Station
No tags
Last refresh of the prices: Today at 11:54 AM EST.
Compare 2 ways to go from Portland to Baltimore
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Baltimore. The journey takes about 15 hours 15 minutes and with fares starting at just $57, it presents an excellent value for a comfortable ride.
Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $83
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Portland, ME to Baltimore by bus
What is the distance between Portland and Baltimore?
About 446 miles (720 km) separate Portland and Baltimore.
What are the departure and arrival stations when taking the bus from Portland to Baltimore?
If you're headed to Baltimore from Portland, chances are that your bus will leave from Greyhound Station Portland Maine and arrive at Baltimore Downtown Bus Station. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Baltimore?
Once in Baltimore, you can start exploring the city and discover its surroundings. The top sights and things to do are Babe Ruth Birthplace Museum, Oriole Park at Camden Yard, National Aquarium, National Great Blacks In Wax Museum and Historic Ships in Baltimore.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/23
$100
11/24
$102
Today
$196
11/26
$189
11/27
$103
11/28
$91
11/29
$97
11/30
$123
The cheapest trip from Portland, ME to Baltimore was searched and found on Nov 28, 2025 with a price of $91
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, ME to Baltimore, as early as possible.
You can expect to pay from $91 to $694 for a bus ticket from Portland, ME to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-11-28.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Portland, ME to Baltimore?
The bus is the cheapest travel choice for this destination