Bus from Detroit, MI to Harrisburg: Tickets & Schedules

Next departures

Next departures for Detroit to Harrisburg on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Detroit Bus Station
Harrisburg Bus StationCheapestFastest
Amtrak
Amtrak Station
Harrisburg, PANo tags
Greyhound Lines, Inc.
Detroit Bus Station
Harrisburg Bus StationNo tags
Amtrak
Amtrak Station
Harrisburg, PANo tags
Greyhound Lines, Inc.
Detroit Bus Station
Harrisburg Bus StationNo tags

Last refresh of the prices: Yesterday at 5:35 PM EST.

Get from Detroit to Harrisburg

This route is served by bus only

The journey takes about 12 hours 10 minutes, and with fares starting at just $126, it presents an excellent value for a comfortable ride.

2bus per day
12h 10mAverage Duration
565 kmDistance
14kgCO₂ emissions

Frequently asked questions about travelling from Detroit, MI to Harrisburg by bus

  1. How far is Detroit from Harrisburg?

    The distance between Detroit and Harrisburg is approximately 564 km (350 miles).

  2. What are the departure and arrival locations for buses traveling from Detroit to Harrisburg?

    Buses departing from Detroit Bus Station in Detroit will take you to Harrisburg Bieber Greyhound Station in Harrisburg.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-25
$178
11-26
$255
Today
$136
11-28
$136
11-29
$201
11-30
$298
12-01
No data
12-02
No data
busbud logoThe cheapest trip from Detroit, MI to Harrisburg was searched and found on Nov 27, 2025 with a price of $136

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Harrisburg, as early as possible.

You can expect to pay from $136 to $936 for a bus ticket from Detroit, MI to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $136 which is on 2025-11-28.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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