Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Detroit Bus Station | Harrisburg Bus Station | CheapestFastest | |||||
 | Amtrak Station | Harrisburg, PA | No tags | |||||
| Detroit Bus Station | Harrisburg Bus Station | No tags | |||||
| Amtrak Station | Harrisburg, PA | No tags | |||||
| Detroit Bus Station | Harrisburg Bus Station | No tags |
Last refresh of the prices: Yesterday at 5:35 PM EST.
Get from Detroit to Harrisburg
The journey takes about 12 hours 10 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Harrisburg?
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
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Frequently asked questions about traveling from Detroit, MI to Harrisburg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Detroit to Harrisburg?
The cheapest bus tickets from Detroit to Harrisburg start from $88. The average price for this route is around $117. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Detroit to Harrisburg?
The average bus trip duration from Detroit to Harrisburg is 12h 10m, covering a distance of 351 miles (565 km). The quickest bus can get you there in 11h 50m and is operated by Greyhound.
Which bus companies service the Detroit to Harrisburg route?
What is the earliest and latest departure time for the bus from Detroit to Harrisburg?
The earliest bus departs from Detroit to Harrisburg at 6:40am. And the latest bus departs at 10:05pm.
What are the CO₂ emissions for the bus trip from Detroit to Harrisburg?
A bus trip from Detroit to Harrisburg generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Detroit to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Detroit to Harrisburg?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Detroit to Harrisburg?
According to Busbud traveller reviews, the most timely bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Detroit to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Harrisburg was searched and found on Nov 27, 2025 with a price of $94To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Harrisburg, as early as possible.
You can expect to pay from $94 to $650 for a bus ticket from Detroit, MI to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-11-28.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
