Next departures for Charleston to Tampa on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Tampa Bus Station
CheapestFastest
Next departures for Charleston to Tampa on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Tampa Bus Station
CheapestFastest
Last refresh of the prices: Yesterday at 3:22 AM EST.
Compare 2 ways to go from Charleston to Tampa
We recommend taking the train
Among the sustainable travel choices, the train stands out as a good way to reach Tampa. The journey takes about 16 hours 50 minutes, and with fares starting at just $104, it presents an excellent value for a comfortable ride.
Based on 11380 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $99
Based on 87384 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $116
Where are the popular stops in Charleston and Tampa?
Stops in Charleston
A - Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Stops in Tampa
A - Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605
B - Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA
C - Greyhound Station
610 E Polk St, Tampa, FL 33602, USA
D - E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA
E - N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA
F - Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Frequently asked questions about travelling from Charleston, SC, US to Tampa by bus
What is the distance between Charleston and Tampa?
The distance between Charleston and Tampa is approximately 591 km (366 miles).
What are the departure and arrival locations for buses traveling from Charleston to Tampa?
Buses departing from Charleston Bus Station in Charleston will take you to Tampa 13th Avenue Bus Stop (McDonald's) in Tampa.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-18
No data
11-19
No data
Today
$106
11-21
$116
11-22
$145
11-23
No data
11-24
$110
11-25
No data
The cheapest trip from Charleston, SC, US to Tampa was searched and found on Nov 20, 2025 with a price of $106
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Tampa, as early as possible.
You can expect to pay from $106 to $145 for a bus ticket from Charleston, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2025-11-24.
What's the cheapest way to go from Charleston, SC, US to Tampa?
The bus is the cheapest travel choice for this destination
The cheapest trip from Charleston, SC, US to Tampa was searched and found on Nov 20, 2025 with a price of $106
The bus is the cheapest travel choice for this destination
