What is the distance between Charleston and Tampa?

Charleston and Tampa are 366 miles (591 km) apart.

What are the departure and arrival stations when taking the bus from Charleston to Tampa?

If you're headed to Tampa from Charleston, chances are that your bus will depart from Charleston Bus Station and arrive at Tampa 13th Avenue Bus Stop (McDonald's). These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.

Bus Charleston to Tampa from $62 | Refundable Tickets

Next bus departures

Next departures for Charleston to Tampa on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:15am	4565 Gaynor Ave, North Charleston	18h 45m	6:00am	Tampa Bus Station	CheapestFastest

Next departures for Charleston to Tampa on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:15am	4565 Gaynor Ave, North Charleston	18h 45m	6:00am	Tampa Bus Station	CheapestFastest

Last refresh of the prices: Today at 5:42 AM EST.

Compare 2 ways to go from Charleston to Tampa

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Tampa. The journey takes about 16 hours 50 minutes and with fares starting at just $72, it presents an excellent value for a comfortable ride.

1train per day

16h 50mAverage Duration

370 milesDistance

54kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$75 - $178	Average Duration18h 45m	CO₂ emissions 15kg CO₂e
Train	Average Price$72 - $519	Average Duration16h 50m	CO₂ emissions 54kg CO₂e

Where are the popular stops in Charleston and Tampa?

Stops in Charleston

A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405

Stops in Tampa

A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605
B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA
C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA
D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA
E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA
F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA

Compare bus companies

FlixBus

3.5/511,444 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Charleston, SC, US to Tampa by bus

What is the distance between Charleston and Tampa?
What are the departure and arrival stations when taking the bus from Charleston to Tampa?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/23

No data

11/24

$76

Today

No data

11/26

$94

11/27

$100

11/28

No data

11/29

$106

11/30

No data

The cheapest trip from Charleston, SC, US to Tampa was searched and found on Nov 24, 2025 with a price of $76

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Tampa, as early as possible.

You can expect to pay from $76 to $106 for a bus ticket from Charleston, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-11-26.