- Chicago to Greenville trains
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Train | Chicago (Union Station), IL | Greenville Station | No tags | ||||
![]() | Train | Chicago (Union Station), IL | Greenville Station | No tags | ||||
![]() | Train | Chicago (Union Station), IL | Greenville Station | No tags | ||||
![]() | Train | Chicago (Union Station), IL | Greenville Station | No tags | ||||
![]() | Train | Chicago (Union Station), IL | Greenville Station | No tags |
Compare 2 ways to go from Chicago to Greenville
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 20 hours 50 minutes and with fares starting at just $96, it presents an excellent value for a comfortable ride.
14bus per day
20h 50mAverage Duration
556 milesDistance
22kgCO₂ emissions
Train Companies
4 out of 5 stars4/55,610 reviews
Based on 5610 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $217
Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo
Frequently asked questions about traveling from Chicago to Greenville, SC by train
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/26
$434
11/27
$360
Today
No data
11/29
No data
11/30
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12/01
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12/02
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12/03
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To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to Greenville, SC, as early as possible.






