Bus from Wilmington, DE to Charleston, SC, US: Tickets & Schedules

Next bus departures

Next departures for Wilmington to Charleston on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Wilmington Bus Station
4565 Gaynor Ave, North CharlestonCheapestFastest

Last refresh of the prices: Yesterday at 8:05 PM EST.

Compare 2 ways to go from Wilmington to Charleston

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 11 hours 39 minutes and with fares starting at just $93, it presents an excellent value for a comfortable ride.

2train per day
11h 39mAverage Duration
534 milesDistance
78kgCO₂ emissions
Average Price$75 - $257Average Duration1d
21kg CO₂e
Average Price$93 - $397Average Duration11h 39m
78kg CO₂e

Frequently asked questions about traveling from Wilmington, DE to Charleston, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Wilmington to Charleston?

    The cheapest bus tickets from Wilmington to Charleston start from $75. The average price for this route is around $107. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Wilmington to Charleston?

    The average bus trip duration from Wilmington to Charleston is 1d , covering a distance of 526 miles (848 km). The quickest bus can get you there in 20h and is operated by Greyhound.

  3. Which bus companies service the Wilmington to Charleston route?

    Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Wilmington to Charleston?

    The earliest bus departs from Wilmington to Charleston at 2:50am. And the latest bus departs at 9:25pm.

  5. What are the CO₂ emissions for the bus trip from Wilmington to Charleston?

    A bus trip from Wilmington to Charleston generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Wilmington to Charleston?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from Wilmington to Charleston?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Wilmington to Charleston?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Wilmington to Charleston?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/26
$210
11/27
$185
Today
$206
11/29
$135
11/30
$128
12/01
$104
12/02
$91
12/03
$82
busbud logoThe cheapest trip from Wilmington, DE to Charleston, SC, US was searched and found on Dec 3, 2025 with a price of $82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Charleston, SC, US, as early as possible.

You can expect to pay from $82 to $210 for a bus ticket from Wilmington, DE to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $82 which is on 2025-12-03.

What's the cheapest way to go from Wilmington, DE to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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