Next departures for Boston to Charleston on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
Next departures for Boston to Charleston on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Cheapest
Bus
Boston (South Station)
4565 Gaynor Ave, North Charleston
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
4565 Gaynor Ave, North Charleston
No tags
FlixBus + Greyhound Lines, Inc.
Bus
151 Steel Pl, Cambridge
4565 Gaynor Ave, North Charleston
No tags
Last refresh of the prices: Today at 12:32 AM EST.
Compare 2 ways to go from Boston to Charleston
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Charleston. The journey takes about 19 hours 38 minutes and with fares starting at just $130, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
FlixBus Boston Charleston recent customer reviews
All 3 buses were on time. Even arrived 10-15 minutes early for connections. Bus drivers were very helpful. I'm disabled & use a walker. 👍
With about 1 daily trips between Boston and Charleston, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
Frequently asked questions about traveling from Boston, MA, US to Charleston, SC, US by bus
What is the travel distance from Boston to Charleston?
Boston and Charleston are 819 miles (1321 km) apart.
What are the departure and arrival stations when taking the bus from Boston to Charleston?
The majority of buses traveling from Boston to Charleston start their journey at Back Bay Station and wind up at Charleston Bus Station. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Charleston?
Once in Charleston, you can start exploring the city and discover its surroundings. The top sights and things to do are Magnolia Plantation and Gardens, Charleston Ghost and Dungeon Tour, On Purpose Adventures, Dock Street Theatre and Gibbes Museum of Art.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
$240
11/22
$258
Today
$340
11/24
$366
11/25
$354
11/26
$310
11/27
$149
11/28
$246
The cheapest trip from Boston, MA, US to Charleston, SC, US was searched and found on Nov 27, 2025 with a price of $149
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Charleston, SC, US, as early as possible.
You can expect to pay from $149 to $366 for a bus ticket from Boston, MA, US to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $149 which is on 2025-11-27.
What's the cheapest way to go from Boston, MA, US to Charleston, SC, US?
The bus is the cheapest travel choice for this destination